merck millipore,默克密理愽
  • merck millipore,默克密理博,14-600M,TAK1-TAB1 fusion Protein, active, 250 µg

  • merck millipore,默克密理博,14-600M,TAK1-TAB1 fusion Protein, active, 250 µg

    产品名称：TAK1-TAB1 fusion Protein, active, 250 µg
    产品型号：14-600M
    Active, N-terminal His6-tagged, recombinant, human TAK1 amino acids 1-303, fused to human TAB1 amino acids 437-end, for use in Kinase Assays.

    merck millipore,默克密理博,14-600M,TAK1-TAB1 fusion Protein, active, 250 µg

  • 产品介绍
  • merck millipore,默克密理博,14-600M,TAK1-TAB1 fusion Protein, active, 250 µg

    描述
    产品目录编号 14-600M
    品牌系列 Upstate
    商名
    • Upstate
    描述 TAK1-TAB1 fusion Protein, active, 250 µg
    概述 N-terminal His6-tagged, recombinant, human TAK1 amino acids 1-303, fused to human TAB1 amino acids 437-end
    应用
    应用 Active, N-terminal His6-tagged, recombinant, human TAK1 amino acids 1-303, fused to human TAB1 amino acids 437-end, for use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 expressed by baculovirus in Sf21 insect cells
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_145333.1
    • NM_003188.2
    • NM_145331.1
    • NM_145332.1
    Entrez基因汇总 The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
    基因符号
    • TGF1a
    • MAP3K7
    • TAK1
    蛋白靶 Tak1
    纯化方法 Ni2+/NTA-agarose
    靶子系列 TKL
    UniProt编号
    • O43318
    UniProt汇总 FUNCTION: SwissProt: O43318 # Component of a protein kinase signal transduction cascade. Mediator of TGF-beta signal transduction. Stimulates NF- kappa-B activation and the p38 MAPK pathway.
    COFACTOR: Magnesium.
    SIZE: 606 amino acids; 67196 Da
    SUBUNIT: Binds both upstream activators and downstream substrates in multimolecular complexes. Interacts with MAP3K7IP1 and MAP3K7IP2. Interacts with PPM1L.
    PTM: Association with MAP3K7IP1 promotes autophosphorylation and subsequent activation.
    SIMILARITY: SwissProt: O43318 ## Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 routinely evaluated by phosphorylation of casein
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -70°C
    包装信息
    数量 250 µg
    包装 Also available in 10 μg size (cat#14-600) and in bulk (cat# 14-600-K).

    merck millipore,默克密理博,14-600M,TAK1-TAB1 fusion Protein, active, 250 µg

上一件merck millipore产品：merck millipore,默克密理博,524742,Phosphodiesterase 3A, Active, Human, Recombinant, S. frugiperda
下一件merck millipore产品：merck millipore,默克密理博,14-500M,Flt-3 Protein, active, 250 µg


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