- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
描述 产品目录编号 14-111 品牌系列 Upstate
商名 - Upstate
描述 PP2A Protein, purified, 10 units 概述 For selective in vitro dephosphorylation of proteins. 应用 应用 10 units of PP2A, purified. For selective in vitro dephosphorylation of proteins. For use in Phosphatase Assays. 主要应用 - Phosphatase Assay
生物信息 来源 Purified from human red blood cells. 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - NM_014225.3
Entrez基因汇总 This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. 基因符号 - MGC786
- PPP2R1A
- PR65A
蛋白靶 PP2A 纯化方法 DEAE chromatography, aminohexyl-agarose and gel filtration chromatography 靶子系列 Ser/Thr phosphatase UniProt编号 - P30153
UniProt汇总 FUNCTION: SwissProt: P30153 # The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.
SIZE: 589 amino acids; 65309 Da
SUBUNIT: PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules. Interacts with IPO9.
DOMAIN: SwissProt: P30153 Each HEAT repeat appears to consist of two alpha helices joined by a hydrophilic region, the intrarepeat loop. The repeat units may be arranged laterally to form a rod-like structure.
SIMILARITY: Belongs to the phosphatase 2A regulatory subunit A family. & Contains 15 HEAT repeats.产品使用声明 质量保证 routinely evaluated by dephosphorylation of proteins 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 1 year at -20 C 包装信息 数量 10 units
上一件merck millipore产品：merck millipore,默克密理博,SCM005,ReNcell NSC Maintenance Media
下一件merck millipore产品：merck millipore,默克密理博,17-10098,ChIPAb+ TATA Binding Protein (TBP) - ChIP Validated Antibody and Primer Set
相关产品
merck millipore,默克密理博,MABD86,Anti-CD349/Frizzled 9 Antibody, clone W3C4
merck millipore,默克密理博,19-134,p38/SAPK2 Inhibitor (SB 202190)
merck millipore,默克密理博,14-670,TSSK1 Protein, active, 10 µg
merck millipore,默克密理博,S7911,Amplifluor FAM-SR Assay Optimization Buffers
merck millipore,默克密理博,SCM005,ReNcell NSC Maintenance Media
merck millipore,默克密理博,SLMP025SS,Millex-GP Med，0.22 µm，改良聚醚砜，25 mm，环氧乙烷灭菌
merck millipore,默克密理博,361569,GSK-3beta Inhibitor XXVI - Calbiochem
merck millipore,默克密理博,AB9626,Anti-Ephrin B phosphoTyr317 Antibody
merck millipore,默克密理博,04-1486,Anti-33D1 (CD8- Mouse DC marker) Antibody, clone 33D1