• merck millipore,默克密理博,14-1050,Human recombinant H3.1 core histone octamers
  • merck millipore,默克密理博,14-1050,Human recombinant H3.1 core histone octamers

    产品名称:Human recombinant H3.1 core histone octamers
    产品型号:14-1050
    Human recombinant core histones H2A, H2B, H3.1 & H4, expressed in E Coli & purified by Fast Protein Liquid Chromatography.

    merck millipore,默克密理博,14-1050,Human recombinant H3.1 core histone octamers

  • 产品介绍
  • merck millipore,默克密理博,14-1050,Human recombinant H3.1 core histone octamers

    重要规格表

    主要应用
    ACT
    描述
    产品目录编号 14-1050
    品牌系列 Upstate
    商名
    • Upstate
    描述 Human recombinant H3.1 core histone octamers
    概述 Human recombinant core histones H2A, H2B, H3.1, and H4, expressed in E Coli. and purified by Fast Protein Liquid Chromatography.
    背景信息 The core histones, H2A, H2B, H3, and H4, form a central octameric structure that binds approximately 147 bp of DNA to form a nucleosome. The nucleosome is the first order of DNA compaction in the nucleus, and is the basic unit of chromatin. Chromatin structure can be altered by post-translational modifications (PTM) occurring on the C- and N-terminal tails of H2A, H2B, H3, and H4. Histone modifications can either provide or hinder access of key transcriptional complexes to DNA sequences and can regulate the expression of genes. These effects can be deciphered by applications such as chromatin immunoprecipiation (ChIP), which requires high quality chromatin, and essential tools such as histone proteins and appropriate enzymes, to assemble chromatin in vitro.
    产品信息
    演示 In buffer containing 20 mM Tris-Cl pH 7.9, 1 mM EDTA, 2 M NaCl, 0.5 mM PMSF and 1 mM DTT.
    应用
    应用 Human recombinant core histones H2A, H2B, H3.1 & H4, expressed in E Coli & purified by Fast Protein Liquid Chromatography.
    主要应用
    • Activity Assay
    应用说明 Suitable for in vitro chromatin assembly and enzyme activity assays
    生物信息
    浓缩 1 µg/µL
    宿主 E. coli
    纯度 >98% purity by SDS PAGE
    来源 Human
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable at -80ºC for 1 year from date of receipt.
    包装信息
    数量 25 µg

    merck millipore,默克密理博,14-1050,Human recombinant H3.1 core histone octamers

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