• merck millipore,默克密理博,123040,AICA-Riboside - CAS 2627-69-2 - Calbiochem
  • merck millipore,默克密理博,123040,AICA-Riboside - CAS 2627-69-2 - Calbiochem

    产品名称:AICA-Riboside - CAS 2627-69-2 - Calbiochem
    产品型号:123040
    A cell-permeable nucleoside compound whose phosphorylated metabolite activates adenosine monophosphate-activated protein kinase (AMPK) and acts as a regulator of de novo purine synthesis.

    merck millipore,默克密理博,123040,AICA-Riboside - CAS 2627-69-2 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,123040,AICA-Riboside - CAS 2627-69-2 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₉H₁₄N₄O₅2627-69-2
    描述
    概述 A cell-permeable nucleoside compound whose phosphorylated metabolite activates adenosine monophosphate-activated protein kinase (AMPK) and acts as a regulator of de novo purine synthesis. Stimulates glucose uptake in perfused and isolated muscle. Offers protection against cell death induced by glucose deprivation, chemical hypoxia, and exposure to glutamate and Aβ peptide.
    产品目录编号 123040
    品牌系列 Calbiochem®
    同义词 Acadesine, AICAr, 5-Aminoimidazole-4-carboxamide-1-β-riboside, Z-Riboside, AMPK Signaling Activator II
    参考
    参考 Meli, M., et al. 2006. J. Med. Chem. in press.
    Culmsee, C., et al. 2001. J. Mol. Neurosci. 17, 45.
    Muoio, D.M., et al. 1999. Biochem. J. 338, 783.
    Hayashi, T., et al. 1998. Diabetes 47, 1369.
    Corton, J.M., et al. 1995. Eur. J. Biochem. 229, 558.
    产品信息
    CAS号 2627-69-2
    具有ATP竞争性 N
    形式 Tan solid
    Hill配方 C₉H₁₄N₄O₅
    化学配方 C₉H₁₄N₄O₅
    Molar Mass 258.2
    可逆 N
    结构配方图像
    生物信息
    主靶 Adenosine monophosphate-activated protein kinase (AMPK)
    纯度 ≥98% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 MeOH or H₂O
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,123040,AICA-Riboside - CAS 2627-69-2 - Calbiochem

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