• 产品介绍

  • 描述
    产品目录编号 12-516
    品牌系列 Upstate
    商名
    • Upstate
    描述 Axltide
    产品信息
    演示 Lyophilized powder
    应用
    主要应用
    • Kinase Assay
    生物信息
    Entrez基因编号
    • NM_021913.2
    • NM_001699.3
    Entrez基因汇总 The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
    基因符号
    • UFO
    • AXL
    蛋白靶 Axl
    靶子系列 TK
    UniProt编号
    • P30530
    UniProt汇总 FUNCTION: SwissProt: P30530 # May function as a signal transducer between specific cell types of mesodermal origin.
    SIZE: 887 amino acids; 97437 Da
    SUBUNIT: Heterodimer and heterotetramer with GAS6.
    SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
    DISEASE:SwissProt: P30530 # Has transforming potential in patients with chronic myeloproliferative disorder or chronic myelocytic leukemia.
    SIMILARITY: SwissProt: P30530 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. AXL/UFO subfamily. & Contains 2 fibronectin type-III domains. & Contains 2 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 Routinely evaluated by for use as a substrate in protein kinase assay.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 2 years at -20°C
    包装信息
    数量 1 mg


上一件merck millipore产品:merck millipore,默克密理博,AB10526,Anti-COX4 Antibody
下一件merck millipore产品:merck millipore,默克密理博,AB15616,Anti-Neurogenin-1 Antibody



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