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merck millipore,默克密理博,116812,Adenosine 3ʹ,5ʹ-cyclic Monophosphate, 8-(4-Chlorophenylthio)-, Sodium Salt - CAS 93882-12-3 - Calbiochem
产品名称：Adenosine 3ʹ,5ʹ-cyclic Monophosphate, 8-(4-Chlorophenylthio)-, Sodium Salt - CAS 93882-12-3 - Calbiochem
产品型号：116812
Cell-permeable cAMP analog that activates both protein kinase A and protein kinase G.
merck millipore,默克密理博,116812,Adenosine 3ʹ,5ʹ-cyclic Monophosphate, 8-(4-Chlorophenylthio)-, Sodium Salt - CAS 93882-12-3 - Calbiochem
- 产品介绍
- merck millipore,默克密理博,116812,Adenosine 3ʹ,5ʹ-cyclic Monophosphate, 8-(4-Chlorophenylthio)-, Sodium Salt - CAS 93882-12-3 - Calbiochem
重要规格表
经验配方 CAS号 C₁₆H₁₄ClN₅O₆PS · Na 93882-12-3 描述 概述 Cell-permeable cAMP analog that activates both protein kinase A and protein kinase G. Directly activates Epac, a Rap1 guanine-nucleotide exchange factor. Also acts as a potent inhibitor of cGMP-specific phosphodiesterase (IC50 = 900 nM). Inhibits cAMP-specific phosphodiesterase at much higher concentrations (IC50 = 25 µM). 产品目录编号 116812 品牌系列 Calbiochem®
同义词 Adenosine 3ʹ,5ʹ-cyclic Monophosphate, 8-(4-Chlorophenylthio)-, Sodium Salt 参考 参考 de Rooij, J., et al. 1998. Nature. 396, 474.
Kawasaki, H., et al. 1998. Science. 282, 2275.
Moed, P.J., et al. 1993. Comp. Biochem. Physiol. 105A, 711.
Connolly, B.J., et al. 1992. Biochem. Pharmacol. 44, 2303.
Phillips, M.E., and Taylor, A. 1992. J. Physiol. 456, 591.
Shipston, M.J., and Antoni, F.A. 1992. Endocrinology 130, 2213.
Datta, R., et al. 1991. Blood 78, 83.
Peters, D.J.M., et al. 1991. Proc. Natl. Acad. Sci. USA 88, 9219.
Sandberg, M., et al. 1991. Biochem. J. 279, 521.
Unterman, T.G., et al. 1991. Endocrinology 128, 2693.
Xu, H., et al. 1989. Brain Res. 504, 36.产品信息 CAS号 93882-12-3 具有ATP竞争性 N 形式 White solid Hill配方 C₁₆H₁₄ClN₅O₆PS · Na 化学配方 C₁₆H₁₄ClN₅O₆PS · Na Molar Mass 493.8 吸湿 Hygroscopic
可逆 N 结构配方图像 生物信息 主靶 Protein kinase A and protein kinase G 主靶IC50 900 nM against cGMP-specific phosphodiesterase 纯度 ≥98% by HPLC 理化信息 细胞可渗透 Y 溶解度 H₂O 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C
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