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merck millipore,默克密理博,116805,PKA Inhibitor 5-24 - CAS 99534-03-9 - Calbiochem
产品名称:PKA Inhibitor 5-24 - CAS 99534-03-9 - Calbiochem
产品型号:116805
The PKA Inhibitor 5-24, also referenced under CAS 99534-03-9, controls the biological activity of PKA. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applicati More>>
merck millipore,默克密理博,116805,PKA Inhibitor 5-24 - CAS 99534-03-9 - Calbiochem
- 产品介绍
- merck millipore,默克密理博,116805,PKA Inhibitor 5-24 - CAS 99534-03-9 - Calbiochem
重要规格表
经验配方 CAS号 C₉₄H₁₄₈N₃₂O₃₁ 99534-03-9 描述 概述 A potent synthetic peptide that is a competitive inhibitor of protein kinase A (Ki = 2.3 nM). Its sequence is derived from the heat-stable skeletal muscle inhibitor protein of PKA. Binds to the catalytic subunit of PKA and displaces the regulatory subunit. Mimics the protein substrate by binding to the catalytic site via the arginine-cluster basic substrate. 产品目录编号 116805 品牌系列 Calbiochem®
同义词 Protein Kinase A Inhibitor 5-24, H-TTYADFIASGRTGRRNAIHD, PKA Inhibitor IV 参考 参考 Knighton, D.R., et al. 1991. Science 253, 525.
Cheng, H.C., et al. 1986. J. Biol. Chem. 261, 989.
Rusine, T., et al. 1986. J. Cell Biol. 102, 1630.
Wong, Y.S., et al. 1986. J. Biol. Chem.12089. 产品信息 CAS号 99534-03-9 具有ATP竞争性 N 形式 Lyophilized 配方 Supplied as a trifluoroacetate salt. Sold on the basis of peptide content. Hill配方 C₉₄H₁₄₈N₃₂O₃₁ 化学配方 C₉₄H₁₄₈N₃₂O₃₁ Molar Mass 2222.4 吸湿 Hygroscopic
肽序列 H-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp-OH 可逆 N 基于肽含量售出 Yes
生物信息 主靶 PKA 主靶Ki 2.3 nM for protein kinase A 纯度 ≥95% by HPLC 理化信息 细胞可渗透 N 溶解度 H₂O 肽含量 Yes
肽序列 H-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp-OH 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
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