• merck millipore,默克密理博,116805,PKA Inhibitor 5-24 - CAS 99534-03-9 - Calbiochem
  • merck millipore,默克密理博,116805,PKA Inhibitor 5-24 - CAS 99534-03-9 - Calbiochem

    产品名称:PKA Inhibitor 5-24 - CAS 99534-03-9 - Calbiochem
    产品型号:116805
    The PKA Inhibitor 5-24, also referenced under CAS 99534-03-9, controls the biological activity of PKA. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applicati More>>

    merck millipore,默克密理博,116805,PKA Inhibitor 5-24 - CAS 99534-03-9 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,116805,PKA Inhibitor 5-24 - CAS 99534-03-9 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₉₄H₁₄₈N₃₂O₃₁99534-03-9
    描述
    概述 A potent synthetic peptide that is a competitive inhibitor of protein kinase A (Ki = 2.3 nM). Its sequence is derived from the heat-stable skeletal muscle inhibitor protein of PKA. Binds to the catalytic subunit of PKA and displaces the regulatory subunit. Mimics the protein substrate by binding to the catalytic site via the arginine-cluster basic substrate.
    产品目录编号 116805
    品牌系列 Calbiochem®
    同义词 Protein Kinase A Inhibitor 5-24, H-TTYADFIASGRTGRRNAIHD, PKA Inhibitor IV
    参考
    参考 Knighton, D.R., et al. 1991. Science 253, 525.
    Cheng, H.C., et al. 1986. J. Biol. Chem. 261, 989.
    Rusine, T., et al. 1986. J. Cell Biol. 102, 1630.
    Wong, Y.S., et al. 1986. J. Biol. Chem. 12089.
    产品信息
    CAS号 99534-03-9
    具有ATP竞争性 N
    形式 Lyophilized
    配方 Supplied as a trifluoroacetate salt. Sold on the basis of peptide content.
    Hill配方 C₉₄H₁₄₈N₃₂O₃₁
    化学配方 C₉₄H₁₄₈N₃₂O₃₁
    Molar Mass 2222.4
    吸湿 Hygroscopic
    肽序列 H-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp-OH
    可逆 N
    基于肽含量售出 Yes
    生物信息
    主靶 PKA
    主靶Ki 2.3 nM for protein kinase A
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 H₂O
    肽含量 Yes
    肽序列 H-Thr-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-His-Asp-OH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.

    merck millipore,默克密理博,116805,PKA Inhibitor 5-24 - CAS 99534-03-9 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,ECM670,QCM™ Gelatin Invadopodia Assay (Green)
下一件merck millipore产品:merck millipore,默克密理博,345805,Geldanamycin, Streptomyces hygroscopicus - CAS 30562-34-6 - Calbiochem



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