• merck millipore,默克密理博,114810,ADAMTS-5 Inhibitor - CAS 929634-33-3 - Calbiochem
  • merck millipore,默克密理博,114810,ADAMTS-5 Inhibitor - CAS 929634-33-3 - Calbiochem

    产品名称:ADAMTS-5 Inhibitor - CAS 929634-33-3 - Calbiochem
    产品型号:114810
    The ADAMTS-5 Inhibitor, also referenced under CAS 929634-33-3, controls the biological activity of ADAMTS-5. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

    merck millipore,默克密理博,114810,ADAMTS-5 Inhibitor - CAS 929634-33-3 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,114810,ADAMTS-5 Inhibitor - CAS 929634-33-3 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₆H₁₁ClF₃N₃OS₃929634-33-3
    描述
    概述 A thioxothiazolidinone compound that possesses a Zn2+-chelating structural motif and acts as an ADAMTS-5 (aggrecanase-2) inhibitor (IC50 = 1.1 µM) with ~40-fold selectivity over ADAMTS-4 (aggrecanase-1).
    产品目录编号 114810
    品牌系列 Calbiochem®
    同义词 5-((4-Chlorobenzylthio-3-trifluoromethyl-N-methyl-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one, Aggrecanase-2 Inhibitor
    参考
    参考 Bursavich, M.G., et al. 2007. Bioorg. Med. Chem. Lett. 17, 1185.
    Gilbert, A.M., et al. 2007. Bioorg. Med. Chem. Lett. 17, 1189.
    产品信息
    CAS号 929634-33-3
    具有ATP竞争性 N
    形式 Yellow solid
    Hill配方 C₁₆H₁₁ClF₃N₃OS₃
    化学配方 C₁₆H₁₁ClF₃N₃OS₃
    Molar Mass 449.9
    可逆 N
    结构配方图像
    生物信息
    主靶 ADAMTS-5
    纯度 ≥97% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO
    安全信息
    R相 R: 22-36/37/38

    Harmful if swallowed.
    Irritating to eyes, respiratory system and skin.
    S相 S: 36/37

    Wear suitable protective clothing and gloves.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,114810,ADAMTS-5 Inhibitor - CAS 929634-33-3 - Calbiochem

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