• merck millipore,默克密理博,100081,14-3-3 Antagonist I, 2-5 - Calbiochem
  • merck millipore,默克密理博,100081,14-3-3 Antagonist I, 2-5 - Calbiochem

    产品名称:14-3-3 Antagonist I, 2-5 - Calbiochem
    产品型号:100081
    The 14-3-3 Antagonist I, 2-5 controls the biological activity of 14-3-3.

    merck millipore,默克密理博,100081,14-3-3 Antagonist I, 2-5 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,100081,14-3-3 Antagonist I, 2-5 - Calbiochem

    重要规格表

    经验配方
    C₂₀H₂₃N₆O₈P
    描述
    概述 A cell-permeable dipeptidyl-phosphoserine compound that effectively disrupts 14-3-3 interaction with its ligands (IC50 = 2.6 µM against TMR-GG-RLSHpSSLPG binding to human 14-3-3ς), including Raf-1 and p53. Shown to induce caspase-3 activation and apoptotic cell death in human lung adenocarcinoma A549 cultures (100µM) in a time-dependent manner.
    产品目录编号 100081
    品牌系列 Calbiochem®
    同义词 (S)-2-(2-(4-Azidobenzamido)acetamido)-3-((4-hydroxyphenethyl)amino)-3-oxopropyl-dihydrogen phosphate
    参考
    参考 Wu, H., et al. 2010. Angew. Chem. Int. Ed. 49, 6528.
    产品信息
    形式 Pale yellow to beige solid
    Hill配方 C₂₀H₂₃N₆O₈P
    化学配方 C₂₀H₂₃N₆O₈P
    Molar Mass 506.4
    吸湿 Hygroscopic
    结构配方图像
    生物信息
    纯度 ≥90% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,100081,14-3-3 Antagonist I, 2-5 - Calbiochem

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