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经验配方 C₂₀H₂₃N₆O₈P 描述 概述 A cell-permeable dipeptidyl-phosphoserine compound that effectively disrupts 14-3-3 interaction with its ligands (IC50 = 2.6 µM against TMR-GG-RLSHpSSLPG binding to human 14-3-3ς), including Raf-1 and p53. Shown to induce caspase-3 activation and apoptotic cell death in human lung adenocarcinoma A549 cultures (100µM) in a time-dependent manner. 产品目录编号 100081 品牌系列 Calbiochem®
同义词 (S)-2-(2-(4-Azidobenzamido)acetamido)-3-((4-hydroxyphenethyl)amino)-3-oxopropyl-dihydrogen phosphate 参考 参考 Wu, H., et al. 2010. Angew. Chem. Int. Ed. 49, 6528. 产品信息 形式 Pale yellow to beige solid Hill配方 C₂₀H₂₃N₆O₈P 化学配方 C₂₀H₂₃N₆O₈P Molar Mass 506.4 吸湿 Hygroscopic
结构配方图像 生物信息 纯度 ≥90% by HPLC 理化信息 溶解度 DMSO 储存和货运信息 货运代码 Shipped with Blue Ice or with Dry Ice
毒性 Standard Handling
储存 -20°C
避光 Protect from light
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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