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品种反应性 主要应用 宿主 格式 抗体类型 H, M WB Rb Purified Polyclonal Antibody 描述 产品目录编号 09-030 描述 Anti-CBX6 Antibody Alternate Names - chromobox homolog 6
背景信息 The family of Heterochromatin Proteins ("Chromobox Homolog", CBX) are highly conserved adapter molecules, which have important functions in the cell nucleus. These functions include gene repression by heterochromatin formation, transcriptional activation, regulation of binding of cohesion complexes to centromere, sequesteration of genes to nuclear periphery, transcriptional arrest, maintenance of heterochromatin integrity, gene repression at single nucleosome level and gene repression by heterochromatization of euchromatin. 产品信息 格式 Purified 控制 - NIH/3T3 cell lysate
演示 Purified rabbit polyclonal in buffer containing PBS and 0.05% sodium azide. 应用 应用 Anti-CBX6 Antibody is a Rabbit Polyclonal Antibody for detection of CBX6 also known as chromobox homolog 6 & has been validated in WB. 主要应用 - Western Blotting
应用说明 SNAP I.D. (western blotting technique): A previous lot of this antibody worked successfully using the SNAP I.D. western blotting device and technique. 生物信息 免疫原品种 GST-tagged recombinant protein corresponding to the postchromo domain of CBX6. 表位 Postchromo Domain 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody detects the postchromo domain of CBX6. 品种反应性 HumanMouse Species Reactivity Note Mouse. Predicted to react with human based on sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_083039.2
基因符号 - OTTHUMP00000028667
纯化方法 Protein A purifed with GST depletion UniProt编号 - Q9DBY5
UniProt汇总 FUNCTION: Involved in maintaining the transcriptionally repressive state of genes. Modifies chromatin, rendering it heritably changed in its expressibility By similarity.
SUBUNIT STRUCTURE: Component of the chromatin-associated polycomb complex (PcG) By similarity.
SUBCELLULAR LOCATION: NucleusBy similarity.
SEQUENCE SIMILARITIES: Contains 1 chromo domain.
产品使用声明 质量保证 Evaluated by western blot on NIH/3T3 cell lysate.
Western Blot Analysis: 0.5-2 µg/mL of this antibody detected CBX6 in NIH/3T3 cell lysate.
使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8ºC from date of receipt. 包装信息 数量 100 µg
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