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merck millipore,默克密理博,ABS485,Anti-phospho LEF Antibody (Thr155)
产品名称:Anti-phospho LEF Antibody (Thr155)
产品型号:ABS485
Anti-phospho LEF Antibody (Thr155) is a highly specific rabbit polyclonal antibody, that targets LEF-1 (lymphoid Enhancer Factor 1) & has been tested in western blotting & Peptide Inhibition Assay.
merck millipore,默克密理博,ABS485,Anti-phospho LEF Antibody (Thr155)
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABS485 描述 Anti-phospho LEF Antibody (Thr155) Alternate Names - TCF1A
- Lymphoid enhancer-binding factor 1
- LEF-1
- T cell-specific transcription factor 1-alpha
- TCF1-alpha
背景信息 Lymphoid enhancer factor, LEF-1, is a transcription factor of the High Mobility Group of DNA binding proteins. It is one member of a family of four proteins referred to as LEF/TCF transcription factors (LEF-1, TCF-1, TCF-3, and TCF-4). These factors play crucial roles in WNT/Wingless signaling, a signal transduction cascade that directs cell differentiation. Aberrant activation of the WNT/Wingless pathway is also a root cause in the genesis of certain cancers such as colon cancer, melanoma, and breast cancer. LEF-1 is expressed during development in many different differentiating tissues, and in a few tissues after birth. LEF-1 expression is required for proper development of breast, teeth, hair, whiskers, and the trigeminal nerve. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal serum in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-phospho LEF Antibody (Thr155) is a highly specific rabbit polyclonal antibody, that targets LEF-1 (lymphoid Enhancer Factor 1) & has been tested in western blotting & Peptide Inhibition Assay. 主要应用 - Western Blotting
应用说明 Western Blotting/Peptide Inhibition Analysis: 0.02 µg/mL from a representative lot detected phospho LEF (Thr155) in 10 µg of Jurkat cell lysate treated with Calyculin A and Okadaic acid. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the Proline Rich Domain of human LEF1 phosphorylated at Thr155. 表位 Proline Rich Domain 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human Species Reactivity Note Predicted to react with Mouse, Rat, Bovine, Chicken, Porcine, Xenopus, and Zebrafish based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_057353
基因符号 - LEF1
纯化方法 Affinity purified UniProt编号 - Q9UJU2
产品使用声明 质量保证 Evaluated by Western Blotting in Jurkat cell lysate treated with Calyculin A and Okadaic acid
Western Blotting Analysis: 0.02 µg/mL of this antibody detected phospho LEF (Thr155) in 10 µg of Jurkat cell lysate treated with Calyculin A and Okadaic acid.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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