merck millipore,默克密理愽
  • merck millipore,默克密理博,07-716-I,Anti-KDR/Flk-1/VEGFR2 Antibody

  • merck millipore,默克密理博,07-716-I,Anti-KDR/Flk-1/VEGFR2 Antibody

    产品名称：Anti-KDR/Flk-1/VEGFR2 Antibody
    产品型号：07-716-I
    Detect KDR/Flk-1/VEGFR2 using this rabbit polyclonal antibody, Anti-KDR/Flk-1/VEGFR2 Antibody validated for use in western blotting.

    merck millipore,默克密理博,07-716-I,Anti-KDR/Flk-1/VEGFR2 Antibody

  • 产品介绍
  • merck millipore,默克密理博,07-716-I,Anti-KDR/Flk-1/VEGFR2 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    H, MWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 07-716-I
    Replaces 07-716
    描述 Anti-KDR/Flk-1/VEGFR2 Antibody
    Alternate Names
    • CD309
    • Vascular endothelial growth factor receptor 2
    • VEGFR-2
    • Fetal liver kinase 1
    • FLK-1
    • Kinase NYK
    • Protein-tyrosine kinase receptor flk-1
    背景信息 The Flt gene family of receptor tyrosine kinases includes Flt-1, KDR/Flk-1, Flt-3, and Flt-4. They encode receptors for VEGF, characterized by seven Ig-loops within their extracellular domain and a split kinase domain within the cytoplasmic domain. VEGF is an important angiogenic factor of many solid tumors and is also involved in the differentiation of endothelial cells. Flt-1 (Fms-like tyrosine kinase, VEGF-R1) is expressed on endothelial cells and on the common precursors of endothelial and hematopoietic stem cells. KDR (Flk-1, VEGF-R2) is the principal receptor involved in VEGF signaling. KDR is expressed on endothelial cells and stimulates angiogenesis, but is also expressed on bone marrow cells, and is thought to play a role in driving the proliferation of most or all leukemic cells. Flt3 is a class III receptor tyrosine kinase that is closely related to c-Kit and c-Fms. It is expressed in primitive hematopoietic cells and its ligand exerts proliferative effects on these cells in co-operation with other cytokines. The VEGF receptors stimulate the Ras-MAP kinase pathway, suggesting that it signals as a conventional receptor tyrosine kinase.
    产品信息
    格式 Affinity Purified
    演示 Purified rabbit Polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Detect KDR/Flk-1/VEGFR2 using this rabbit polyclonal antibody, Anti-KDR/Flk-1/VEGFR2 Antibody validated for use in western blotting.
    主要应用
    • Western Blotting
    应用说明 Western Blotting Analysis: A 1:500 dilution from a representative lot detected KDR/Flk-1/VEGFR2 in 10 µg of PAE cells transfected with CSF/VEGFR2 chimera.
    生物信息
    免疫原品种 GST-tagged recombinant protein corresponding to the C-terminus of mouse KDR/Flk-1/VEGFR2.
    表位 C-terminus
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    品种反应性 HumanMouse
    抗体类型 Polyclonal Antibody
    基因符号
    • Flk1
    • Kdr
    • Flk-1
    纯化方法 Affinity purified
    UniProt编号
    • P35918
    产品使用声明
    质量保证 Evaluated by Western Blotting in HUVEC cell lysate.

    Western Blotting Analysis: 1.0 µg/mL of this antibody detected KDR/Flk-1/VEGFR2 in 10 µg of HUVEC cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,07-716-I,Anti-KDR/Flk-1/VEGFR2 Antibody

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