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  • merck millipore,默克密理博,07-680,Anti-Histone H2B Antibody, testis variant

  • merck millipore,默克密理博,07-680,Anti-Histone H2B Antibody, testis variant

    产品名称：Anti-Histone H2B Antibody, testis variant
    产品型号：07-680
    Anti-Histone H2B Antibody, testis variant is a Rabbit Polyclonal Antibody for detection of Histone H2B also known as Histone H2B & has been tested in WB.

    merck millipore,默克密理博,07-680,Anti-Histone H2B Antibody, testis variant

  • 产品介绍
  • merck millipore,默克密理博,07-680,Anti-Histone H2B Antibody, testis variant

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, HWBRbSerumPolyclonal Antibody
    描述
    产品目录编号 07-680
    Replaces MABE15
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-Histone H2B Antibody, testis variant
    产品信息
    格式 Serum
    应用
    应用 Anti-Histone H2B Antibody, testis variant is a Rabbit Polyclonal Antibody for detection of Histone H2B also known as Histone H2B & has been tested in WB.
    主要应用
    • Western Blotting
    生物信息
    免疫原品种 KLH-conjugated, synthetic peptide spanning amino acids 7-17 (...GATISKKGFKK...) of human testis/sperm specific histone H2B
    宿主 Rabbit
    特异性 histone H2B, testis variant
    品种反应性 MouseHuman
    Species Reactivity Note Predicted to cross-react with rat based on sequence homology
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_170610.2
    Entrez基因汇总 Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a testis/sperm-specific member of the histone H2B family. Transcripts from this gene contain a palindromic termination element.
    基因符号
    • TSH2B
    • HIST1H2BA
    • H2BFU
    • bA317E16.3
    • STBP
    纯化方法 Antiserum
    UniProt编号
    • Q96A08
    UniProt汇总 FUNCTION: SwissProt: Q96A08 # Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    SIZE: 127 amino acids; 14167 Da
    SUBUNIT: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
    SUBCELLULAR LOCATION: Nucleus.
    TISSUE SPECIFICITY: Transcribed exclusively in testis, and the corresponding protein is also present in mature sperm.
    PTM: Monoubiquitination of Lys-122 by the RNF20/40 complex gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation. It also functions cooperatively with the FACT dimer to stimulate elongation by RNA polymerase II.
    SIMILARITY: SwissProt: Q96A08 ## Belongs to the histone H2B family.
    产品使用声明
    质量保证 routinely evaluated by immunoblot in whole cell extracts from mouse testis cells.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 stable 2 years at -20°C from date of shipment
    包装信息
    数量 100 µL

    merck millipore,默克密理博,07-680,Anti-Histone H2B Antibody, testis variant

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