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merck millipore,默克密理博,07-1285,Anti-acetylated-Src (Lys430) Antibody
产品名称：Anti-acetylated-Src (Lys430) Antibody
产品型号：07-1285
This Anti-acetylated-Src (Lys430) Antibody is validated for use in WB, Cell Function Assay for the detection of acetylated-Src (Lys430).
merck millipore,默克密理博,07-1285,Anti-acetylated-Src (Lys430) Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 07-1285 描述 Anti-acetylated-Src (Lys430) Antibody Alternate Names - SRC
背景信息 Src is a proto-oncogenic tyrosine kinase belonging to the Src family of non-receptor tyrosine kinases. This proto-oncogene plays a pivotal role cellular processes such as proliferation, migration, transformation and regulation of embyronic development and cell growth. Src tyrosine kinases transmit integrin-dependent signals for cell movement and proliferation. The study of Src proteins have contributed to the understanding of cancer caused by abnormal cellular signaling. 产品信息 格式 Affinity Purified 控制 - HEK293T cells transfected with myc-tagged Src and CBP
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 This Anti-acetylated-Src (Lys430) Antibody is validated for use in WB, Cell Function Assay for the detection of acetylated-Src (Lys430). 主要应用 - Western Blotting
应用说明 Western Blot Analysis: 5 µg/mL from a representative lot detected Src on 10 µg of HEK293T cells transfected with myc-tagged Src and CBP. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human Src acetylated at Lys430. 表位 Acetylated Lys430 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes Src acetylated at Lys430. 品种反应性 RatHumanMouse Species Reactivity Note Demonstrated to react with Human.
Predicted to react with Rat and Mouse based on 100% sequence homology.抗体类型 Polyclonal Antibody Entrez基因编号 - NP_005408
基因符号 - c-SRC
- Src1
- c-src
- p60-Src
- SRC1
修改 - Acetylation
纯化方法 Affinity purified UniProt编号 - P12931
UniProt汇总 SIZE: 536 amino acids; 59835 Da
SUBUNIT: Interacts with DDEF1/ASAP1 via its SH3 domain. Interacts with CCPG1 (By similarity). Interacts with CDCP1, PELP1, TGFB1I1 and TOM1L2.
PTM: Phosphorylated on Tyr-530 by c-Src kinase (CSK). The phosphorylated form is termed pp60c-src. The phosphorylated tail interacts with the SH2 domain thereby repressing kinase activity.
SIMILARITY: Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.产品使用声明 质量保证 Western Blot/Peptide Inhibition Assay Analysis: This antibody peptide blocked on HEK293T cells transfected with myc-tagged Src and CBP. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,MABC741,Anti-RIPK2, clone EPR4224(2), Rabbit Monoclonal Antibody
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