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品种反应性 主要应用 宿主 格式 抗体类型 H WB, ICC Rb Serum Polyclonal Antibody 描述 产品目录编号 07-001 品牌系列 Upstate
商名 - Upstate
描述 Anti-p47-phox Antibody 产品信息 格式 Serum 控制 - HL-60 cell lysate
演示 Immunoaffinity Purified immunoglobulin in 0.2M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide, 5mg/ml BSA before the addition of glycerol to 30% 应用 应用 Anti-p47-phox Antibody detects level of p47-phox & has been published & validated for use in IC, IP & WB. 主要应用 - Western Blotting
- Immunocytochemistry
生物信息 免疫原品种 GST fusion protein corresponding to full-length human p47-phox 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes p47 phox. 同种型 IgG 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_000265
Entrez基因汇总 The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. 基因符号 - NCF-1
- NCF1
- NCF-47K
- NOXO2
- p47-phox
- SH3PXD1A
- NCF1A
- p47phox
纯化方法 Unpurified UniProt编号 - P14598
UniProt汇总 FUNCTION: SwissProt: P14598 # NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).
SIZE: 390 amino acids; 44683 Da
SUBCELLULAR LOCATION: Cytoplasm.
DISEASE:SwissProt: P14598 # Defects in NCF1 are the cause of autosomal cytochrome-b- positive chronic granulomatous disease type 1 (CGD) [MIM:233700]; an autosomal recessive form.
SIMILARITY: SwissProt: P14598 ## Contains 1 PX (phox homology) domain. & Contains 2 SH3 domains.产品使用声明 质量保证 routinely evaluated by immunoblot on RIPA lysates from HL-60 cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 包装信息 数量 200 µL
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