- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Po, B, H, M WB Gt Purified Polyclonal Antibody 描述 产品目录编号 06-127 品牌系列 Upstate
商名 - Upstate
描述 Anti-PDGF Antibody, neutralizing 产品信息 格式 Purified 应用 应用 Anti-PDGF Antibody, neutralizing detects level of PDGF & has been published & validated for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 Purified human PDGF-AB; recognizes PDGF AA, AB and BB. 宿主 Goat 同种型 IgG 品种反应性 PigBovineHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_033023, NM_033016, NM_016205
Entrez基因汇总 The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis; knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene. 基因符号 - PDGF1
- PDGFA
- PDGF-1
- PDGF-A
纯化方法 DEAE chromatography UniProt编号 - P01127
- P04085
UniProt汇总 FUNCTION: SwissProt: P04085 # Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
SIZE: 211 amino acids; 24043 Da
SUBUNIT: Antiparallel disulfide-linked dimer of non-identical (A and B) chains. Homodimers of A and B chains are implicated in transformation processes. Interacts with CSPG4.
SUBCELLULAR LOCATION: Secreted.
DOMAIN: SwissProt: P04085 The long form contains a basic insert which acts as a cell retention signal.SIMILARITY: Belongs to the PDGF/VEGF growth factor family.
MISCELLANEOUS: A-A and B-B, as well as A-B, dimers can bind to the PDGF receptor.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 1 mg
上一件merck millipore产品：merck millipore,默克密理博,ABT347,Anti-CDH23 Antibody
下一件merck millipore产品：merck millipore,默克密理博,OP33,Anti-p53 (Ab-5) (Wild type) Mouse mAb (PAb1620)
相关产品
merck millipore,默克密理博,AB5388,Anti-Synphilin-1 Antibody, a.a. 829-847
merck millipore,默克密理博,MAB1285-KC,Anti HLA-B27, Clone.ABC.M3 Purified (KC)
merck millipore,默克密理博,MZPHN0W50,MultiScreenHTS 384 PH，0.65 µm，不透明，非无菌
merck millipore,默克密理博,OP91,Anti-Bcl-2 (Ab-3) Mouse mAb (4D7)
merck millipore,默克密理博,ABT347,Anti-CDH23 Antibody
merck millipore,默克密理博,OP33,Anti-p53 (Ab-5) (Wild type) Mouse mAb (PAb1620)
merck millipore,默克密理博,06-559,Anti-Pyk2 Antibody
merck millipore,默克密理博,MAB4316,Mouse Anti-Rex-1 Antibody
merck millipore,默克密理博,MABN250,Anti-RA-induced protein 17 Antibody, clone 5H5.1
