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品种反应性 主要应用 宿主 格式 抗体类型 M, H WB M Culture Supernatant Monoclonal Antibody 描述 产品目录编号 05-941 品牌系列 Upstate
商名 - Upstate
描述 Anti-PTPA Antibody, clone 5G3 产品信息 格式 Culture Supernatant 应用 应用 Detect PTPA using this Anti-PTPA Antibody, clone 5G3 validated for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 Full length mouse phosphotyrosyl phosphatase activator protein (PTPA) 克隆 clone 5G3 宿主 Mouse 特异性 PTPA 品种反应性 MouseHuman 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_178001
Entrez基因汇总 Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. 基因符号 - PP2A
- PPP2R4
- PR53
- KIAA0044
- PTPA
- MGC2184
UniProt编号 - Q15257
UniProt汇总 FUNCTION: SwissProt: Q15257 # Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer in presence of ATP and Mg(2+) (in vitro).
SIZE: 358 amino acids; 40668 Da
SUBUNIT: Associates with PP2A heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A).
TISSUE SPECIFICITY: Widely expressed.
SIMILARITY: SwissProt: Q15257 ## Belongs to the PTPA-type PPIase family.产品使用声明 质量保证 Routinely evaluated by immunoblot detecting PTPA in RIPA lysates from HeLa cells. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C from date of shipment 包装信息 数量 100 µL
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