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merck millipore,默克密理博,05-860,Anti-Vitronectin Antibody, clone GMA-900
产品名称：Anti-Vitronectin Antibody, clone GMA-900
产品型号：05-860
Detect Vitronectin using this Anti-Vitronectin Antibody, clone GMA-900 validated for use in ELISA & WB.
merck millipore,默克密理博,05-860,Anti-Vitronectin Antibody, clone GMA-900
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB, ELISA M Purified Monoclonal Antibody 描述 产品目录编号 05-860 Replaces 04-1108 品牌系列 Upstate
商名 - Upstate
描述 Anti-Vitronectin Antibody, clone GMA-900 产品信息 格式 Purified 应用 应用 Detect Vitronectin using this Anti-Vitronectin Antibody, clone GMA-900 validated for use in ELISA & WB. 主要应用 - Western Blotting
- ELISA
生物信息 免疫原品种 Purified human vitronectin 克隆 GMA-900 宿主 Mouse 特异性 Vitronectin 同种型 IgG2a 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_000638
Entrez基因汇总 The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. 基因符号 - V75
- VTN
- S-protein
- VNT
- VN
- epibolin
纯化方法 DEAE purified UniProt编号 - P04004
UniProt汇总 FUNCTION: SwissProt: P04004 # Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.
SIZE: 478 amino acids; 54306 Da
SUBUNIT: Exists in two forms: a single chain 75 kDa form (V75) and a clipped form composed of two chains (65 kDa and 10 kDa) (V65+V10) which are held together by a disulfide bond. Interacts with SERPINE1/PAI1 and insulin.
SUBCELLULAR LOCATION: Secreted, extracellular space.
TISSUE SPECIFICITY: Plasma.
DOMAIN: SwissProt: P04004 The SMB domain mediates interaction with SERPINE1/PAI1. The heparin-binding domain mediates interaction with insulin.
PTM: Sulfated on 2 tyrosine residues. & N- and O-glycosylated (By similarity). & Phosphorylation on Thr-69 and Thr-76 favors cell adhesion and spreading. & It has been suggested that the active SMB domain may be permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both.SIMILARITY: Contains 4 hemopexin-like domains. & Contains 1 SMB (somatomedin-B) domain.产品使用声明 质量保证 routinely evaluated by immunoblot on victronectin 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 stable 2 years at -20°C from date of shipment 包装信息 数量 100 µg
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