merck millipore,默克密理博,05-806-AF647,Anti-phospho Histone H3 (Ser10), clone 3H10, Alexa Fluor 647 Antibody

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	ICC	M	AlexaFluor®647	Monoclonal Antibody

描述
产品目录编号	05-806-AF647
描述	Anti-phospho Histone H3 (Ser10), clone 3H10, Alexa Fluor® 647 Antibody
Alternate Names	H3 histone, family 3B (H3.3B) H3 histone, family 3A, H3S10P Histone H3 (phospho S10) H3 histone, family 3A H3 histone, family 3B
背景信息	Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Histone proteins are highly post-translationally modified, and Histone H3 is the most extensively modified of the five histones. Histone H3 sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Di- and tri-methylation of histone H3 are gene silencing marks, while removal of these marks by the demethylase genes Jmjd1a and Jmjd2c leads to gene activation. This product is a conjugated version of Cat. No. 05-806.

产品信息
格式	AlexaFluor®647
演示	Purified mouse conjugated antibody in buffer containing PBS and 15 mg/ml BSA with 0.1% Sodium Azide.

应用
应用	This Anti-phospho Histone H3 (Ser10) antibody, clone 3H10, Alexa Fluor® 647 is a purified mouse monoclonal for detection of Histone H3 phosphorylated at serine 10. This mAb is fluorescently labeled and validated for use in IC. The unconjugated version has been proven in FC, ICC, IF, PIA, WB, Mplex.
主要应用	Immunocytochemistry

生物信息
免疫原品种	Linear peptide corresponding to Histone H3 phosphorylated at Ser10.
宿主	Mouse
品种反应性	Human
抗体类型	Monoclonal Antibody
Entrez基因编号	NM_003493
基因符号	MGC126886 HIST1H3A H3FA HIST1H3B H3FL HIST1H3C H3FC HIST1H3D H3FB HIST1H3E H3FD HIST1H3F H3FI HIST1H3G H3FH HIST1H3H H3FK HIST1H3I H3FF HIST1H3J H3FJ HIST3H3 H3FT H3T
纯化方法	Protein G purified
UniProt编号	Q16695

产品使用声明
质量保证	Evaluated by Immunocytochemistry Analysis in HeLa cells. Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected phospho Histone H3 (Ser10) in HeLa cells. Alexa Fluor® is a registered trademark of Life Technologies®.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µL

merck millipore,默克密理博,05-806-AF647,Anti-phospho Histone H3 (Ser10), clone 3H10, Alexa Fluor 647 Antibody

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