- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB, ICC M Ascites Monoclonal Antibody 描述 产品目录编号 05-758 品牌系列 Upstate
商名 - Upstate
描述 Anti-FE65 Antibody, clone 3H6 产品信息 格式 Ascites 控制 - Alzheimer's diseased brains
演示 Immunoaffinity Purified immunoglobulin in 0.2M Tris-glycine, pH 7.2, 0.15M NaCl, 0.05% sodium azide with 5mg/ml BSA 应用 应用 Anti-FE65 Antibody, clone 3H6 detects level of FE65 & has been published & validated for use in IC, IP & WB. 主要应用 - Western Blotting
- Immunocytochemistry
生物信息 免疫原品种 GST fusion protein corresponding to amino acids 254-293 of mouse FE65, WW domain 克隆 3H6 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 Recognizes FE65. 同种型 IgG 品种反应性 RatHumanMouse 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_001164
Entrez基因汇总 The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants have been described for this gene but some of their full length sequence is not known. 基因符号 - Fe65
- APBB1
- RIR
- FE65
- MGC:9072
纯化方法 Unpurified UniProt编号 - O00213
UniProt汇总 FUNCTION: SwissProt: O00213 # May modulate the internalization of beta-amyloid precursor protein.
SIZE: 710 amino acids; 77244 Da
SUBUNIT: Binds to the intracellular domain of the beta-amyloid precursor protein. Interacts, through the WW domain, with proline- rich regions of APBB1IP and ENAH (By similarity).
TISSUE SPECIFICITY: Highly expressed in brain.
SIMILARITY: SwissProt: O00213 ## Contains 2 PID domains. & Contains 1 WW domain.产品使用声明 质量保证 Routinely evaluated by immunoblot on homogenates prepared from whole mouse, rat and human Alzheimers diseased brains 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 包装信息 数量 100 µL
上一件merck millipore产品：merck millipore,默克密理博,ABT281,Anti-Lactadherin/MFGE8 Antibody
下一件merck millipore产品：merck millipore,默克密理博,567028,SIN-1, Hydrochloride - CAS 16142-27-1 - Calbiochem
相关产品
merck millipore,默克密理博,200980,Bikinin - CAS 188011-69-0 - Calbiochem
merck millipore,默克密理博,444218,MMP-3 Inhibitor I - Calbiochem
merck millipore,默克密理博,14-785M,PI3 Kinase (p110α/p85α) murine, 250 µg
merck millipore,默克密理博,SF-1518,MBNL1; Human, Cyanine 5 RNA Detection Probe,SmartFlare
merck millipore,默克密理博,ABT281,Anti-Lactadherin/MFGE8 Antibody
merck millipore,默克密理博,567028,SIN-1, Hydrochloride - CAS 16142-27-1 - Calbiochem
merck millipore,默克密理博,05-1075,Anti-FOXO1 Antibody, clone 2H8.2
merck millipore,默克密理博,ABN165,Anti-MMEL1 Antibody
![merck millipore,默克密理博,04-1123,Anti-CD44 [H-CAM] Antibody, clone EPR1013Y, rabbit monoclonal](/e/upload/m_pic/04-1123_IHP%5B04-1123_IHP-ALL%5D.jpg "merck millipore,默克密理博,04-1123,Anti-CD44 [H-CAM] Antibody, clone EPR1013Y, rabbit monoclonal")
merck millipore,默克密理博,04-1123,Anti-CD44 [H-CAM] Antibody, clone EPR1013Y, rabbit monoclonal
merck millipore,默克密理博,AB15810,Anti-Substance P Receptor Antibody