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merck millipore,默克密理博,05-643,Anti-phospho-GSK3β (Ser9) Antibody, clone 2D3
产品名称：Anti-phospho-GSK3β (Ser9) Antibody, clone 2D3
产品型号：05-643
Anti-phospho-GSK3β (Ser9) Antibody, clone 2D3 is an antibody against phospho-GSK3β (Ser9) for use in EMSA & WB.
merck millipore,默克密理博,05-643,Anti-phospho-GSK3β (Ser9) Antibody, clone 2D3
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB, EMSA M Purified Monoclonal Antibody 描述 产品目录编号 05-643 Replaces 04-1075 品牌系列 Upstate
商名 - Upstate
描述 Anti-phospho-GSK3β (Ser9) Antibody, clone 2D3 产品信息 格式 Purified 演示 100µg of thiophilic and size exclusion chromatography purified mouse IgG1κ in 100µL of antibody storage buffer (PBS with PEG, Sucrose, and 0.09% sodium azide) and 50% glycerol. 应用 应用 Anti-phospho-GSK3β (Ser9) Antibody, clone 2D3 is an antibody against phospho-GSK3β (Ser9) for use in EMSA & WB. 主要应用 - Western Blotting
- Electrophoretic Mobility Shift Assay
生物信息 免疫原品种 peptide corresponding to amino acids 6-12 (RTT[pS]AE) of human GSK3beta 克隆 2D3 宿主 Mouse 特异性 GSK3beta 同种型 IgG1κ 品种反应性 RatHumanMouse 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_002093
Entrez基因汇总 Glycogen synthase kinase-3 (GSK3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. Two isoforms, alpha (GSK3A; MIM 606784) and beta, show a high degree of amino acid homology (Stambolic and Woodgett, 1994 [PubMed 7980435]). GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation (Plyte et al., 1992 [PubMed 1333807]).[supplied by OMIM] 基因符号 - GSK3B
修改 - Phosphorylation
纯化方法 Thiophilic adsorption chromatography UniProt编号 - P49841
UniProt汇总 FUNCTION: SwissProt: P49841 # Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA.
SIZE: 420 amino acids; 46744 Da
SUBUNIT: Monomer (By similarity). Interacts with NIN and CABYR.
TISSUE SPECIFICITY: Expressed in testis, thymus, prostate and ovary and weakly expressed in lung, brain and kidney.
PTM: Phosphorylated by AKT1 and ILK1.
SIMILARITY: SwissProt: P49841 ## Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily. & Contains 1 protein kinase domain.产品使用声明 质量保证 routinely evaluated by immunoblot on L6 cells stimulated with IGF-1 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,14-936,NEK9, active
下一件merck millipore产品：merck millipore,默克密理博,14-607M,PIM2 Protein, active, 250 µg
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