merck millipore,默克密理愽
  • merck millipore,默克密理博,05-587,Anti-phospho-Adducin (Ser724) Antibody, clone pADD

  • merck millipore,默克密理博,05-587,Anti-phospho-Adducin (Ser724) Antibody, clone pADD

    产品名称：Anti-phospho-Adducin (Ser724) Antibody, clone pADD
    产品型号：05-587
    Detect phospho-Adducin (Ser724) using this Anti-phospho-Adducin (Ser724) Antibody, clone pADD validated for use in IP, WB & IC.

    merck millipore,默克密理博,05-587,Anti-phospho-Adducin (Ser724) Antibody, clone pADD

  • 产品介绍
  • merck millipore,默克密理博,05-587,Anti-phospho-Adducin (Ser724) Antibody, clone pADD

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    R, H, MICC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 05-587
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-phospho-Adducin (Ser724) Antibody, clone pADD
    产品信息
    格式 Purified
    演示 0.7M Tris-glycine, pH 7.4, 0.105M NaCl, 0.035% sodium azide and 30% glycerol.
    应用
    应用 Detect phospho-Adducin (Ser724) using this Anti-phospho-Adducin (Ser724) Antibody, clone pADD validated for use in IP, WB & IC.
    主要应用
    • Immunocytochemistry
    • Western Blotting
    生物信息
    免疫原品种 peptide (FRTP[pS]FLKK) corresponding to amino acids 720-728 of rat phospho-α-Adducin (Ser724)
    克隆 pADD
    宿主 Mouse
    特异性 phospho-Adducin isoforms
    同种型 IgG
    品种反应性 RatHumanMouse
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_001119 and others
    Entrez基因汇总 Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
    基因符号
    • MGC3339
    • ADD1
    • ADDA
    • Alpha-adducin
    • MGC44427
    修改
    • Phosphorylation
    纯化方法 Protein G chromatography
    UniProt编号
    • P35611
    UniProt汇总 FUNCTION: SwissProt: P35611 # Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin.
    SIZE: 737 amino acids; 80955 Da
    SUBUNIT: Heterodimer of an alpha and a beta subunit or an alpha and a gamma subunit. Binds ROCK1.
    SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton.
    TISSUE SPECIFICITY: Expressed in all tissues. Found in much higher levels in reticulocytes than the beta subunit.
    DOMAIN: SwissProt: P35611 Each subunit is comprised of three regions: a NH2-terminal protease-resistant globular head region, a short connecting subdomain, and a protease-sensitive tail region.
    PTM: The N-terminus is blocked.
    SIMILARITY: Belongs to the aldolase class II family. Adducin subfamily.
    产品使用声明
    质量保证 routinely evaluated by immunoblot on lysates from human red blood cells stimulated with PMA
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 2 years at -20°C
    包装信息
    数量 100 µg

    merck millipore,默克密理博,05-587,Anti-phospho-Adducin (Ser724) Antibody, clone pADD

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