- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, H WB M Purified Monoclonal Antibody 描述 产品目录编号 05-550 品牌系列 Upstate
商名 - Upstate
描述 Anti-Cdc6 Antibody, clone DCS-180 产品信息 格式 Purified 演示 10mM PBS, pH 7.4 and 0.05% sodium azide 应用 应用 Detect Cdc6 with Anti-Cdc6 Antibody, clone DCS-180 (Mouse Monoclonal Antibody), that has been shown to work in IP & WB. 主要应用 - Western Blotting
生物信息 免疫原品种 Recombinant, full-length human cdc6 克隆 clone DCS-180 宿主 Mouse 特异性 cdc6 同种型 IgG1 品种反应性 MouseHuman 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_001254
Entrez基因汇总 The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. 基因符号 - CDC18L
- CDC6
- HsCDC18
- cdc6
- HsCDC6
- p62
纯化方法 Protein G chromatography UniProt编号 - Q99741
UniProt汇总 FUNCTION: SwissProt: Q99741 # Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
SIZE: 560 amino acids; 62720 Da
SUBUNIT: Interacts with PCNA, ORC1L and cyclin-CDK.
SUBCELLULAR LOCATION: Nucleus. Cytoplasm. Note=The protein is nuclear in G1 and cytoplasmic in S-phase cells.
SIMILARITY: SwissProt: Q99741 ## Belongs to the CDC6/cdc18 family.产品使用声明 质量保证 routinely evaluated by immunoblot on HeLa nuclear extract or 3T3 nuclear extract 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,371970,HA 1077, Dihydrochloride - CAS 103745-39-7 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,07-876,Anti-phospho-PKCη (Ser674) Antibody
相关产品
merck millipore,默克密理博,CBL1345,Anti-Integrin α2 Antibody, clone HMα2
merck millipore,默克密理博,ST1604,Anti-ADAMTS1 Mouse pAb (1B8)
merck millipore,默克密理博,MAB1406,Anti-Thy-1.1 Antibody, clone OX-7
merck millipore,默克密理博,371970,HA 1077, Dihydrochloride - CAS 103745-39-7 - Calbiochem
merck millipore,默克密理博,07-876,Anti-phospho-PKCη (Ser674) Antibody
merck millipore,默克密理博,ABT185,Anti-Spectrin beta chain Antibody, erythrocyte
merck millipore,默克密理博,567152,β-Sitosterol - CAS 83-46-5 - Calbiochem
merck millipore,默克密理博,CBL490,Anti-Integrin αV Antibody, clone 13C2
merck millipore,默克密理博,71577,pTriEx™-7 Ek/LIC Vector Kit - Novagen