merck millipore,默克密理愽
  • merck millipore,默克密理博,CBL1345,Anti-Integrin α2 Antibody, clone HMα2

  • merck millipore,默克密理博,CBL1345,Anti-Integrin α2 Antibody, clone HMα2

    产品名称：Anti-Integrin α2 Antibody, clone HMα2
    产品型号：CBL1345
    Anti-Integrin α2 Antibody, clone HMα2 detects level of Integrin α2 & has been published & validated for use in FC, IF, IP, IH.

    merck millipore,默克密理博,CBL1345,Anti-Integrin α2 Antibody, clone HMα2

  • 产品介绍
  • merck millipore,默克密理博,CBL1345,Anti-Integrin α2 Antibody, clone HMα2

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    MIHC, FCAHmPurifiedMonoclonal Antibody
    描述
    产品目录编号 CBL1345
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Integrin α2 Antibody, clone HMα2
    Alternate Names
    • CD49b
    背景信息 The complex of CD49b associated with CD29 (integrin beta1) is a receptor for laminin and collagen. This complex is expressed by some CD4-positive T cells, natural killer cells, epithelial cells and platelets.
    产品信息
    格式 Purified
    演示 The affinity chromatography purified monoclonal is presented in phosphate buffered saline, pH 7.2, containing 0.09% sodium azide. We recommend that each laboratory determine an optimum working titre for use in its particular application.
    应用
    应用 Anti-Integrin α2 Antibody, clone HMα2 detects level of Integrin α2 & has been published & validated for use in FC, IF, IP, IH.
    主要应用
    • Immunohistochemistry
    • Flow Cytometry
    应用说明 FlowCytometry: = .5 μg per 10e6 cells in 100 μL volume

    Immunoprecipitation

    Immunofluorescence

    Immunohistochemistry

    Optimal working dilutions must be determined by the end user.
    生物信息
    克隆 HMalpha2
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Armenian Hamster
    特异性 Specifically recognizes the 150 kDa mouse CD49b, also known as Integrin alpha2.
    同种型 IgG
    品种反应性 Mouse
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_002203.3
    Entrez基因汇总 This gene product belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. They are found on a wide variety of cell types including, T cells, fibroblasts and platelets. Integrins are involved in cell adhesion and also participate in cell-surface mediated signalling.
    基因符号
    • GPIa
    • ITGA2
    • CD49B
    • VLAA2
    • VLA-2
    • CD49b
    • BR
    UniProt编号
    • P17301
    UniProt汇总 FUNCTION: SwissProt: P17301 # Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
    SIZE: 1181 amino acids; 129295 Da
    SUBUNIT: Heterodimer of an alpha and a beta subunit. Alpha-2 associates with beta-1. Interacts with HPS5.
    SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
    DOMAIN: SwissProt: P17301 The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
    SIMILARITY: Belongs to the integrin alpha chain family. & Contains 7 FG-GAP repeats. & Contains 1 VWFA domain.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at 2-8°C for up to 12 months from date of receipt.
    包装信息
    数量 500 µg

    merck millipore,默克密理博,CBL1345,Anti-Integrin α2 Antibody, clone HMα2

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