merck millipore,默克密理愽
  • merck millipore,默克密理博,05-517,Anti-PTH/PTHrP Receptor Antibody, clone 3D1.1

  • merck millipore,默克密理博,05-517,Anti-PTH/PTHrP Receptor Antibody, clone 3D1.1

    产品名称：Anti-PTH/PTHrP Receptor Antibody, clone 3D1.1
    产品型号：05-517
    Anti-PTH/PTHrP Receptor Antibody, clone 3D1.1 is an antibody against PTH/PTHrP Receptor for use in IH & WB.

    merck millipore,默克密理博,05-517,Anti-PTH/PTHrP Receptor Antibody, clone 3D1.1

  • 产品介绍
  • merck millipore,默克密理博,05-517,Anti-PTH/PTHrP Receptor Antibody, clone 3D1.1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Po, H, MWB, IHCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 05-517
    品牌系列 Upstate
    商名
    • Upstate
    描述 Anti-PTH/PTHrP Receptor Antibody, clone 3D1.1
    产品信息
    格式 Purified
    控制
    • Kidney Tissue
    演示 Protein G Purified immunoglobulin in Immunoaffinity Purified immunoglobulin in 0.2M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
    应用
    应用 Anti-PTH/PTHrP Receptor Antibody, clone 3D1.1 is an antibody against PTH/PTHrP Receptor for use in IH & WB.
    主要应用
    • Western Blotting
    • Immunohistochemistry
    生物信息
    免疫原品种 Synthetic peptide corresponding to amino acids 146-169 of the human PTH/PTHrP (parathyroid hormone/parathyroid hormone related protein) receptor (RRCDRNGSWELVPGHNRTWANYSE).
    克隆 3D1.1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Recognizes PTH/PTHrP receptor and the receptor dimer.
    同种型 IgG1κ
    品种反应性 PigHumanMouse
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_000315
    Entrez基因汇总 The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone.
    基因符号
    • PTH-rP
    • PTHLH
    • PTHRP
    • osteostatin
    • PTHrP
    • MGC14611
    • PTHR
    • 107-139).
    • PLP
    • HHM
    纯化方法 Protein G purfied
    UniProt编号
    • P12272
    UniProt汇总 FUNCTION: SwissProt: P12272 # Osteostatin is a potent inhibitor of osteoclastic bone resorption.
    SIZE: 177 amino acids; 20194 Da
    SUBCELLULAR LOCATION: Cytoplasm. Nucleus. Secreted.
    TISSUE SPECIFICITY: Ubiquitous. Also expressed in the mammary gland.
    PTM: There are 3 principal secretory forms, called PTHrP[1-36], PTHrP[38-94], and osteostatin (PTHrP[107-139]) arising from endoproteolytic cleavage of the initial translation product. Each of these secretory forms is believed to have one or more of its own receptors that mediates the normal paracrine, autocrine and endocrine actions.
    DISEASE:SwissProt: P12272 # Produced by many tumors from patients with HHM (humoral hypercalcemia of malignancy).
    SIMILARITY: SwissProt: P12272 ## Belongs to the parathyroid hormone family.
    产品使用声明
    质量保证 Routinely evaluated by immunoblot on RIPA lysates of 3T3-L1 pre-adipose fibroblasts
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
    包装信息
    数量 200 µg

    merck millipore,默克密理博,05-517,Anti-PTH/PTHrP Receptor Antibody, clone 3D1.1

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