merck millipore,默克密理愽
  • merck millipore,默克密理博,05-1416,Anti-CD45 Antibody, clone IBL-5/25

  • merck millipore,默克密理博,05-1416,Anti-CD45 Antibody, clone IBL-5/25

    产品名称：Anti-CD45 Antibody, clone IBL-5/25
    产品型号：05-1416
    Anti-CD45 Antibody, clone IBL-5/25 is an antibody against CD45 for use in FC, IH.

    merck millipore,默克密理博,05-1416,Anti-CD45 Antibody, clone IBL-5/25

  • 产品介绍
  • merck millipore,默克密理博,05-1416,Anti-CD45 Antibody, clone IBL-5/25

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    MIHC, FCRPurifiedMonoclonal Antibody
    描述
    产品目录编号 05-1416
    Replaces CBL1326
    描述 Anti-CD45 Antibody, clone IBL-5/25
    Alternate Names
    • protein tyrosine phosphatase, receptor type, c<br />polypeptide-associated protein
    • protein tyrosine phosphatase, receptor type, C-associated protein
    • PTPRC-associated protein
    • Lymphocyte phosphatase-associated phosphoprotein
    • CD45-associated protein
    • CD45 associated protein
    背景信息 CD45 is a receptor-tyrosine phosphatase required for antigen-induced signaling in T-cells and B-cells; its substrates are unknown. Interestingly, it associates with several Src-family tyrosine kinases, which are inhibited by tyrosine phosphorylation in their c-termini, suggesting a mechanism for signaling by CD45.
    产品信息
    格式 Purified
    控制
    • Mouse colon tissue
    演示 Purified rabbit monoclonal IgG in phosphate buffered saline containing 10 mM sodium azide.
    应用
    应用 Anti-CD45 Antibody, clone IBL-5/25 is an antibody against CD45 for use in FC, IH.
    主要应用
    • Immunohistochemistry
    • Flow Cytometry
    应用说明 Flow Cytometry Analysis: A previous lot detected CD45, clone IBL-5/25 in mouse peripheral blood lymphocytes
    生物信息
    免疫原品种 Mouse lymph node cells.
    克隆 IBL-5/25
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rat
    特异性 This antibody reacts with all isoforms of mouse CD45 which is expressed on all haematopoietic cells except erythrocytes.
    FUSION PARTNER: SP2/0 myeloma cell line
    同种型 IgG
    品种反应性 Mouse
    Species Reactivity Note Reacts with mouse. Reactivity with other species has not been determined.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_002829.2
    Entrez基因汇总 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.
    基因符号
    • MGC138603
    • CD45-AP
    • LPAP
    • MGC138602
    纯化方法 Protein G purfied
    UniProt编号
    • Q14761
    UniProt汇总 SUBUNIT STRUCTURE: Interacts with CD45/PTPRC.
    SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein Potential.
    PTM: Phosphorylated on tyrosine residues.
    产品使用声明
    质量保证 Evaluated by Immunohistochemistry in mouse colon tissue.
    Immunohistochemistry Analysis: 1:100 dilution of this antibody detected CD45 in mouse colon tissue.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Store at 2-8°C for 12 months from date of receipt.
    包装信息
    数量 500 µg

    merck millipore,默克密理博,05-1416,Anti-CD45 Antibody, clone IBL-5/25

上一件merck millipore产品：merck millipore,默克密理博,SCGPU02RE,Stericup-GP，0.22 µm，改良聚醚砜，250 mL，射线灭菌
下一件merck millipore产品：merck millipore,默克密理博,AB1254,Anti-Cytochrome P450 Enzyme CYP3A4 Antibody


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