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merck millipore,默克密理博,04-449,Anti-MIP-1 β/CCL4 (CT) Antibody, rabbit monoclonal
产品名称:Anti-MIP-1 β/CCL4 (CT) Antibody, rabbit monoclonal
产品型号:04-449
This Anti-MIP-1 β/CCL4 (C-term) Antibody is validated for use in WB for the detection of MIP-1 β/CCL4 (C-term).
merck millipore,默克密理博,04-449,Anti-MIP-1 β/CCL4 (CT) Antibody, rabbit monoclonal
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Purified Monoclonal Antibody 描述 产品目录编号 04-449 品牌系列 Upstate
商名 - Upstate
描述 Anti-MIP-1 β/CCL4 (CT) Antibody, rabbit monoclonal 产品信息 格式 Purified 演示 In 60% storage buffer (50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 0.01% sodium azide and 0.05% BSA) and 40% glycerol. 应用 应用 This Anti-MIP-1 β/CCL4 (C-term) Antibody is validated for use in WB for the detection of MIP-1 β/CCL4 (C-term). 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated synthetic phosphor-peptide composed of residues at the C-terminus of human MIP-1 beta/CCL4. 宿主 Rabbit 特异性 Recognizes a region composed of residues at the C-terminus of human MIP-1 beta/CCL4. 同种型 IgG 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_002984.2
基因符号 - CCL4L
- CCL4
- 1-69
- G-26
- LAG-1
- MGC126026
- ACT2
- Act-2
- HC21
- SCYA4
- SIS-gamma
- SCYA4L
- MGC104418
- H400
- ACT-2
- MGC126025
- LAG1
- MIP-1-beta
- MIP1B
- AT744.1
- SCYA2
UniProt编号 - P13236
UniProt汇总 FUNCTION: SwissProt: P13236 # Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5- mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.
SIZE: 92 amino acids; 10212 Da
SUBUNIT: Homodimer and heterodimer of MIP-1-alpha(4-69) and MIP-1- beta(3-69).
SUBCELLULAR LOCATION: Secreted.
PTM: N-terminal processed form MIP-1-beta(3-69) is produced by proteolytic cleavage after secretion from peripheral blood lymphocytes.
SIMILARITY: SwissProt: P13236 ## Belongs to the intercrine beta (chemokine CC) family.产品使用声明 质量保证 Routinely evaluated by immunoblot. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 year at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage. 包装信息 数量 100 µL
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