merck millipore,默克密理博,04-1126,Anti-N-cadherin Antibody, CT clone EPR1792Y rabbit monoclonal

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merck millipore,默克密理博,04-1126,Anti-N-cadherin Antibody, CT clone EPR1792Y rabbit monoclonal
产品名称：Anti-N-cadherin Antibody, CT clone EPR1792Y rabbit monoclonal
产品型号：04-1126
Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.

merck millipore,默克密理博,04-1126,Anti-N-cadherin Antibody, CT clone EPR1792Y rabbit monoclonal

产品介绍

merck millipore,默克密理博,04-1126,Anti-N-cadherin Antibody, CT clone EPR1792Y rabbit monoclonal

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
R, H, M	FC, WB, ICC	Rb	Culture Supernatant	Monoclonal Antibody

描述
产品目录编号	04-1126
描述	Anti-N-cadherin Antibody, CT clone EPR1792Y rabbit monoclonal
Alternate Names	calcium-dependent adhesion protein, neuronal CD325 antigen N-cadherin 1 Neural cadherin cadherin 2, N-cadherin (neuronal) cadherin 2, type 1 cadherin 2, type 1, N-cadherin (neuronal)
背景信息	Cadherins constitute a family of transmembrane glycoproteins involved in Ca2+-dependent cell-cell interactions. The members of this family are differentially expressed in various tissues. They function in the maintenance of tissue integrity and morphogenesis. Cadherins are divided into type I and type II subgroups. Type I cadherins include epithelial cadherin (E-cadherin, cadherin-1 or uvomorulin), neural cadherin (N-cadherin or cadherin-2), placental cadherin (P-cadherin or cadherin-3) and retinal cadherin (R-cadherin or cadherin-4), whereas kidney cadherin (K-cadherin or cadherin-6) and osteoblast cadherin (OB-cadherin or cadherin-11) are type II cadherins.

产品信息
格式	Culture Supernatant
控制	C6 cell lysate
演示	Cell culture supernatant containing Rabbit Monoclonal antibody in buffer containing 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl containing 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

应用
应用	Please note that this product will not be available for sale after March 15, 2015. Please select one of the other antibodies against this target.
主要应用	Flow Cytometry Western Blotting Immunocytochemistry
应用说明	Immunohistochemistry Analysis: 1:100 dilution from a previous lot detected N-cadherin in human cervical carcinoma tissue. Immunocytochemistry Analysis: 1:100-250 dilution from a previous lot detected N-cadherin in HeLa cell lysate. Immunoprecipitation: 1:40 dilution from a previous lot was used on IP. Flow Cytometry: 1:30 dilution from a previous lot was used on FC.

生物信息
免疫原品种	Synthetic peptide corresponding to residues on the C-terminus of human N-cadherin.
表位	C-terminus
克隆	EPR1792Y
宿主	Rabbit
特异性	This antibody recognizes N-cadherin.
同种型	IgG
品种反应性	RatHumanMouse
Species Reactivity Note	Human, mouse, and rat.
抗体类型	Monoclonal Antibody
Entrez基因编号	P19022
基因符号	NCAD CD325 CDHN CDw325 N-cadherin
纯化方法	Unpurified
UniProt编号	P19022
UniProt汇总	FUNCTION: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. SUBUNIT STRUCTURE: Interacts with CDCP1. SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. SEQUENCE SIMILARITIES: Contains 5 cadherin domains.

产品使用声明
质量保证	Evaluated by Western Blot on C6 cell lysate. Western Blot Analysis: 1:50,000 dilution of this antibody was used to detect N-cadherin in C6 cell lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20ºC from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20ºC from date of receipt.
Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.