merck millipore,默克密理博,01-309,PDGF-AA Protein, human

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merck millipore,默克密理博,01-309,PDGF-AA Protein, human
产品名称：PDGF-AA Protein, human
产品型号：01-309
The human PDGF-AA Protein is available in a 10 µg format.

merck millipore,默克密理博,01-309,PDGF-AA Protein, human

产品介绍

merck millipore,默克密理博,01-309,PDGF-AA Protein, human

重要规格表

主要应用	品种	来源
CULT	Human	Recombinant human protein produced in E. coli.

描述
产品目录编号	01-309
品牌系列	Upstate
商名	Upstate
描述	PDGF-AA Protein, human

产品信息
演示	Lyophilized with no additives.

应用
应用	The human PDGF-AA Protein is available in a 10 µg format.
主要应用	Cell Culture

生物信息
来源	Recombinant human protein produced in E. coli.
品种	Human
Entrez基因编号	NM_033023.3 NM_002607.4
Entrez基因汇总	The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis; knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene.
基因符号	PDGF1 PDGFA PDGF-1 PDGF-A
物理形式	Lyophilized
纯化方法	Sterilized through a 0.2 micron membrane filter
UniProt编号	P04085
UniProt汇总	FUNCTION: SwissProt: P04085 # Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. SIZE: 211 amino acids; 24043 Da SUBUNIT: Antiparallel disulfide-linked dimer of non-identical (A and B) chains. Homodimers of A and B chains are implicated in transformation processes. Interacts with CSPG4. SUBCELLULAR LOCATION: Secreted. DOMAIN: SwissProt: P04085 The long form contains a basic insert which acts as a cell retention signal.SIMILARITY: Belongs to the PDGF/VEGF growth factor family. MISCELLANEOUS: A-A and B-B, as well as A-B, dimers can bind to the PDGF receptor.

产品使用声明
质量保证	Routinely evaluated in an assay using 3T3/NIH fibroblasts
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Reconstitution: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C. Storage and Stability: : Lyophilized protein is good until expiration date on label if stored at -20°C to -80°C. Rehydrated protein can be stored for 12 months at -20°C to -80°C. Avoid repeated freezing and thawing.

储存和货运信息

存储条件

Reconstitution: Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Storage and Stability: : Lyophilized protein is good until expiration date on label if stored at -20°C to -80°C. Rehydrated protein can be stored for 12 months at -20°C to -80°C. Avoid repeated freezing and thawing.