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主要应用 品种 来源 CULT Mouse Male mouse submaxillary glands 描述 产品目录编号 01-170 品牌系列 Upstate
商名 - Upstate
描述 NGF 7S Protein, mouse 应用 应用 The mouse NGF 7S Protein( or nerve growth factor 7S) is available in a 100 µg format. 主要应用 - Cell Culture
生物信息 来源 Male mouse submaxillary glands 品种 Mouse Entrez基因编号 - NM_002506.2
Entrez基因汇总 This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. 基因符号 - MGC161428
- NGFB
- HSAN5
- NGF
- Beta-NGF
- MGC161426
物理形式 Lyophilized 纯化方法 Sterilized through a 0.2 micron membrane filter UniProt编号 - P01138
UniProt汇总 FUNCTION: SwissProt: P01138 # Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. It stimulates division and differentiation of sympathetic and embryonic sensory neurons.
SIZE: 241 amino acids; 26959 Da
SUBUNIT: Homodimer.
SUBCELLULAR LOCATION: Secreted.
DISEASE: SwissProt: P01138 # Defects in NGFB are the cause of hereditary sensory and autonomic neuropathy type 5 (HSAN5) [MIM:608654]. Hereditary sensory and autonomic neuropathies are characterized by loss of pain sensation in combination with other sensory and/or autonomic abnormalities. HSAN5 patients manifest loss of pain perception and impaired temperature sensitivity, ulcers, and in some cases self- mutilation. The autonomic involvement is variable.
SIMILARITY: SwissProt: P01138 ## Belongs to the NGF-beta family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
包装信息 数量 100 µg
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