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pall,颇尔,LV Centramate 实验室切向流系统,CM018LV, FS007X01, PSM10C11P2, PSM20C11P2, PSM45C11P2, PSM65C11P2, OS001C11P2, OS001T02, OS005C11P2, OS005T02, OS010T02, OS030C11P2, OS030T02, OS050C11P2, OS050T02, OS07
产品名称:LV Centramate 实验室切向流系统
产品型号:CM018LV, FS007X01, PSM10C11P2, PSM20C11P2, PSM45C11P2, PSM65C11P2, OS001C11P2, OS001T02, OS005C11P2, OS005T02, OS010T02, OS030C11P2, OS030T02, OS050C11P2, OS050T02, OS070C11P2, OS070T02, OS100T02, OS300C11P2, OS300T02
pall,颇尔,LV Centramate 实验室切向流系统,CM018LV, FS007X01, PSM10C11P2, PSM20C11P2, PSM45C11P2, PSM65C11P2, OS001C11P2, OS001T02, OS005C11P2, OS005T02, OS010T02, OS030C11P2, OS030T02, OS050C11P2, OS050T02, OS07
- 产品介绍

Designed for Maximum Product Recovery for
Lab-Scale or Scale-Up Process Volumes up to 4 L- 规模扩大/规模缩小装置,用于开发切向流过滤 (TFF) 工艺、生物制药小批量生产、规模缩小调查以及生产安全性和有效性研究材料(一期临床研究)。
- Identical path lengths provide linear scale-up to 颇尔 Centramate and Centrasette™ cassette holders.The LV Centramate holder may be attached to other laboratory TFF systems to improve their scalability characteristics.
- 滞留量低,可从小起始量中获得高浓度的因子。A complete TFF system scalable to full production plant can be optimized using the volumes typically generated in the development or discovery lab.
- 通过采用 316L 抛光不锈钢的鲁尔接口实现轻松连接,以确保实现与生产规模 Centrasette 夹具相同的兼容特性。
- All product-wetted parts comply with pharmaceutical standards.
- Concentration of biomolecules
- Recovery and purification of biomolecules from cell culture supernatants and lysates
- Diafiltration, desalting, and buffer exchange of biomolecules
- Fractionation of mixed molecule solutions
材料成分
- Membrane Cassette Filter Media:Supor® [hydrophilic polyethersulfone (PES)], and Omega™ (low protein-binding, modified PES) membranes
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Cassette Hardware
- Cassette Holder Top and Bottom Plates:Type 316L stainless steel
- Tie Rods and Washers:Type 304 stainless steel
- Nuts:Bronze
尺寸
- Length:22.8 cm (9 in.)Width:8.3 cm (3.3 in.)
Typical Starting Volume
- 0.02 m2 (0.2 ft2) cassette:60 - 4,000 毫升
一般滞留量
- < 1 毫升
Maximum Operating Temperature
- 121 °C (250 °F)
最大操作压力
- 5 bar (500 kPa, 75 psi)
Typical Cross Flow Rate Per 0.02 m2 (0.2 ft2) Cassette (L/min)
- Suspended Screen 0.2 - 0.4
- Screen 0.12 - 0.16
Screen Selection Guideline
- Suspended screen for light-tomoderate particle load solutions
- Screen for optimized processing of particle-free protein solutions to high concentrations
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