pall,颇尔,Heparin HyperD M 肝素亲和层析介质,20029-039, 20029-021, 20029-013

For the Purification of Biological
Molecules that Bind to Heparin

• Design combines the desirable characteristics of a soft, high speed, high capacity hydrogel with the high dimensional stability of a rigid bead
• Leakage is minimized due to the stable chemical link of the heparin molecule to the sorbent
• Rapid packing due to the high density of the bead
• Can be packed in a variety of column sizes

• Enzymes (lipoprotein lipase, coagulation enzymes, superoxide dismutase)
• Growth factors (fibroblast growth factor, Schwan cell growth factor)
• Extracellular matrix proteins (fibronectin, vitronectin)
• Nucleic acid binding protein, hormone receptors, and lipoproteins

Average Particle Size

• 80 微米

Dynamic Binding Capacity for Human ATIII (10% Breakthrough)¹

• > 25 mg/mL

配基

• 猪肝素

Immobilized Heparin/mL Sorbent

• 5 - 10 mg/mL

Working pH

• 3 - 13

Pressure Resistance

• 70 bar (7,000 kPa, 1,000 psi)

Storage Temperature

• 2 - 8 ° C (36 - 46 ° F)

¹Determined using human ATIII at 72.5 UI/mL in 20 mM TrisHCl, 0.3 M NaCl, pH 7.4. Elution with 20 mM Tris HCl, 2 M NaCl, pH 7.4 at a flow rate of 600 cm/h, 10 cm (4 in.) bed height.

Dynamic Binding Capacity vs.Linear Velocity

Column dimensions:0.46 cm I.D. x 10 cm; Sample:HU ATIII at 72.5 μL/mL; Equilibration buffer:20 mM Tris-HCl containing 0.3 M NaCl, pH 7.4.

Pressure vs.Linear Flow Velocity

Column dimensions:0.46 cm I.D. x 10 cm; Buffer:20 mM Tris-HCl containing 0.3 M NaCl, pH 7.4.

材料安全数据表： Heparin HyperD® M 肝素亲和层析介质