merck millipore,默克密理博,SF-918,KLF4; Human, Cyanine 3 RNA Detection Probe,SmartFlare

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Merck Millipore 默克密理愽

Entrez Gene Number	Species Reactivity
NM_004235.4	H

描述
产品目录编号	SF-918
商名	SmartFlare
描述	KLF4; Human, Cyanine 3 RNA Detection Probe \| SmartFlare
Alternate Names	EZF, GKLF
背景信息	With SmartFlare™ RNA Detection probes, you can detect RNA in LIVE CELLS with ease. With just an overnight incubation of KLF4; Human, Cyanine 3 RNA Detection Probe you can detect the presence of KLF4 within your cells. Krüppel-like factors (KLFs) are zinc finger-containing transcription factors with regulatory functions in cell growth, proliferation, differentiation, and embryogenesis. Krüppel-like factor 4 (Klf4) has diverse functionss and acts as both an activator and repressor of transcription. The Klf protein has been shown to activate its own transcription throught its interaction with CACCC core sequences. High expression of Klf4 is observed in differentiating layers of epidermis and a loss of expression results in a break-down of barrier function including protection against pathogen invasion and dehydration. KLF4 is also associated with other biological functions such as proliferation, differentiation and carcinogenesis in gastrointestinal tissues. After DNA damage, Klf4 has been shown to induce DNA repair pathways. Klf4 seems to hinder prostate cancer tumor cell growth and migration.

产品信息
格式	Cyanine 3
演示	Lyophilized

应用
应用	Use SmartFlare RNA Detection probes to measure gene expression in live cells. With an overnight incubation of SmartFlare KLF4, Human, Cyanine 3, you can detect KLF4 RNA levels within your cells.
主要应用	RNA Detection

产品使用声明
质量保证	SmartFlare Probes have been tested in a buffer system to detect the release of the fluorophore in the presence of a complimentary base pair sequence for each lot to confirm target specificity. SmartFlare Probes have also been tested in a cell model system and demonstrated increased fluorescence in cells expressing the target compared to a negative SmartFlare Scramble Control.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Store at 2–8°C in lyophilized format ONLY. Room temperature is required for reconstituted product.

包装信息
数量	250 reactions

merck millipore,默克密理博,SF-918,KLF4; Human, Cyanine 3 RNA Detection Probe,SmartFlare

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