• merck millipore,默克密理博,MABT394,Anti-Plakophilin-2 Antibody, clone 8H6
  • merck millipore,默克密理博,MABT394,Anti-Plakophilin-2 Antibody, clone 8H6

    产品名称:Anti-Plakophilin-2 Antibody, clone 8H6
    产品型号:MABT394
    Anti-Plakophilin-2 Antibody, clone 8H6 detects level of Plakophilin-2 & has been published & validated for use in Western Blotting, ICC.

    merck millipore,默克密理博,MABT394,Anti-Plakophilin-2 Antibody, clone 8H6

  • 产品介绍
  • merck millipore,默克密理博,MABT394,Anti-Plakophilin-2 Antibody, clone 8H6

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HICC, WBMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MABT394
    描述 Anti-Plakophilin-2 Antibody, clone 8H6
    Alternate Names
    • Plakophilin-2
    背景信息 Plakophilin-2 (PKP2) is a member of the Armadillo/β-catenin family. It contains eight ARM repeats and can exist in two slice isoforms (2a and 2b). Plakophilin-2 is highly abundant in simple and stratified epithelial cells; but is also expressed in non-epithelial cells, such as the myocardium and lymph node follicles. In epithelial cells, it is localized to desmosomal plaques and plays an important role in cell-cell adhesion processes. Plakophilin-2 also maintains the cell-cell junctions of cardiac tissue, and is essential for proper cardiac function. Mutations in the plakophilin-2 gene cause arrhythmogenic right ventricular cardiomyopathy 9, a condition characterized by partial breakdown of the myocardium of the right ventricle, electrical instability, and sudden death. Plakophilin-2 has also been implicated in the development of cancer.
    产品信息
    格式 Purified
    控制
    • A431 cell lysate
    演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Anti-Plakophilin-2 Antibody, clone 8H6 detects level of Plakophilin-2 & has been published & validated for use in Western Blotting, ICC.
    主要应用
    • Immunocytochemistry
    • Western Blotting
    应用说明 Immunocytochemistry Analysis: A representative lot was used by an independent laboratory in A431 and UM-SCC-38 cells. (Sobolik-Delmaire, T., et al. (2010). Journal of Investigative Dermatology. 130:2638–2646.)
    生物信息
    免疫原品种 MBP-tagged recombinant protein corresponding to human Plakophilin-2.
    克隆 8H6
    宿主 Mouse
    同种型 IgG1κ
    品种反应性 Human
    Species Reactivity Note Demonstrated to react with Human.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_004563
    基因符号
    • PKP2
    纯化方法 Protein G purified
    UniProt编号
    • Q99959
    产品使用声明
    质量保证 Evaluated by Western Blot in A431 cell lysate.

    Western Blot Analysis: A 1:1,000 dilution of this antibody detected Plakophilin-2 in 10 µg of A431 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,MABT394,Anti-Plakophilin-2 Antibody, clone 8H6

上一件merck millipore产品:merck millipore,默克密理博,SF-823,miR-186-5p; Human, Cyanine 5, RNA Detection Probe,SmartFlare
下一件merck millipore产品:merck millipore,默克密理博,12-460,Dimethyl-Histone H3 (Lys4) Peptide, biotin conjugate



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