merck millipore,默克密理博,MABS750,Anti-Aromatase, clone EPR4534(2), Rabbit Monoclonal Antibody

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merck millipore,默克密理博,MABS750,Anti-Aromatase, clone EPR4534(2), Rabbit Monoclonal Antibody
产品名称：Anti-Aromatase, clone EPR4534(2), Rabbit Monoclonal Antibody
产品型号：MABS750
This Anti-Aromatase, clone EPR4534(2), Rabbit Monoclonal Antibody is validated for use in Western Blotting and Flow Cytometry for the detection of Aromatase.

merck millipore,默克密理博,MABS750,Anti-Aromatase, clone EPR4534(2), Rabbit Monoclonal Antibody

产品介绍

merck millipore,默克密理博,MABS750,Anti-Aromatase, clone EPR4534(2), Rabbit Monoclonal Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	FC, WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABS750
描述	Anti-Aromatase, clone EPR4534(2), Rabbit Monoclonal Antibody
Alternate Names	Estrogen synthase Cytochrome P-450AROM CYPXIX Aromatase Cytochrome P450 19A1
背景信息	Human Aromatase is a membrane-bound enzyme that is localized on the endoplasmic reticulum. While it is found in gonads and adrenal glands where it converts androgens into estrogens in a classical endocrine manner, it is also expressed in various tissues where it regulates local estrogen levels or estrogen/androgen ratios in an intracrine manner. Human Aromatase is known to have two major forms, characterized by one amino acid difference at amino acid position 264 [arginine (264R) and cysteine (264C)]. Abnormal Aromatase hyperactivity is a known cause for Aromatase excess syndrome (AES), which is characterized by excess levels of estrogen, heterosexual precocity in adolescent males and isosexual precocity in adolescent females. On the other hand, Aromatase deficiency (AROD) in Aromatase-deficient (ArKO) mice leads to increased adiposity, an inability to synthesize estrogen, birth defects, and genital-related developmental disorders. It is also reported to play a role in a complex immune-neuro-endocrine network management system in murine cysticercosis.

产品信息
格式	Unpurified
演示	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

应用
应用	This Anti-Aromatase, clone EPR4534(2), Rabbit Monoclonal Antibody is validated for use in Western Blotting and Flow Cytometry for the detection of Aromatase.
主要应用	Flow Cytometry Western Blotting
应用说明	Flow Cytometry Analysis: A 1:100-500 dilution from a representative lot detected Aromatase in NIH:OVCAR-3 cells. Produced in collaboration with Epitomics™

生物信息
免疫原品种	Synthetic peptide corresponding to human Aromatase.
克隆	EPR4534(2)
浓缩	Please refer to lot specific datasheet.
宿主	Rabbit
同种型	IgG
品种反应性	Human
Species Reactivity Note	Human
抗体类型	Monoclonal Antibody
基因符号	CYP19 CYP19A1 ARO1 CYAR
纯化方法	Unpurified
UniProt编号	P11511

产品使用声明
质量保证	Evaluated by Western Blotting in human placneta, human uterus, JAR, and NIH:OVCAR-3 lysates. Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected Aromatase in human placneta, human uterus, JAR, and NIH:OVCAR-3 lysates.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.