merck millipore,默克密理博,MABS748,Anti-phospho-B-Raf (Ser729), clone EPR2207, Rabbit Monoclonal Antibody

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merck millipore,默克密理博,MABS748,Anti-phospho-B-Raf (Ser729), clone EPR2207, Rabbit Monoclonal Antibody
产品名称：Anti-phospho-B-Raf (Ser729), clone EPR2207, Rabbit Monoclonal Antibody
产品型号：MABS748
This Anti-phospho-B-Raf (Ser729), clone EPR2207, Rabbit Monoclonal Antibody is validated for use in Western Blotting for the detection of phospho-B-Raf (Ser729).

merck millipore,默克密理博,MABS748,Anti-phospho-B-Raf (Ser729), clone EPR2207, Rabbit Monoclonal Antibody

产品介绍

merck millipore,默克密理博,MABS748,Anti-phospho-B-Raf (Ser729), clone EPR2207, Rabbit Monoclonal Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
R	WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABS748
描述	Anti-phospho-B-Raf (Ser729), clone EPR2207, Rabbit Monoclonal Antibody
Alternate Names	Serine/threonine-protein kinase B-raf
背景信息	Serine/threonine-protein kinase B-raf, also known as Proto-oncogene B-Raf or p94 or v-Raf murine sarcoma viral oncogene homolog B1, and encoded by the gene name BRAF or BRAF1 or RAFB1, is a Serine/Threonine protein kinase member of the Raf family which includes Raf-1 and A-Raf. B-Raf is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. Composed of three conserved region (CR1, CR2, CR3) B-Raf is expressed primarily in the brain and in the nervous system. It has been observed that MAPK is activated by B-Raf in response to nerve growth factor. More than 60% of malignant melanomas were found to contain a specific mutation, B-Raf (V599E) the product of which possesses constitutive kinase activity. Mutations in B-Raf have also been identified in lung cancer and non-Hodgkin lymphoma.

产品信息
格式	Unpurified
演示	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

应用
应用	This Anti-phospho-B-Raf (Ser729), clone EPR2207, Rabbit Monoclonal Antibody is validated for use in Western Blotting for the detection of phospho-B-Raf (Ser729).
主要应用	Western Blotting
应用说明	Produced in collaboration with Epitomics™

生物信息
免疫原品种	Synthetic peptide corresponding to human phospho-B-Raf (Ser729).
克隆	EPR2207
浓缩	Please refer to lot specific datasheet.
宿主	Rabbit
同种型	IgG
品种反应性	Rat
Species Reactivity Note	Rat
抗体类型	Monoclonal Antibody
基因符号	RAFB1 BRAF BRAF1
纯化方法	Unpurified
UniProt编号	P15056

产品使用声明
质量保证	Evaluated by Western Blotting in PC-12 untreated and PC-12 treated with Lambda Phosphatase cell lysates. Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected phospho-B-Raf (Ser729) in PC-12 untreated and PC-12 treated with Lambda Phosphatase cell lysates.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.