merck millipore,默克密理博,MABS270,Anti-PP2A reg. subunit B56 epsilon (PPP2R5E) Antibody, clone 5A5-1F3

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
M, H	ICC, WB	M	Purified	Monoclonal Antibody

描述
产品目录编号	MABS270
描述	Anti-PP2A reg. subunit B56 epsilon (PPP2R5E) Antibody, clone 5A5-1F3
Alternate Names	PP2A B subunit isoform R5-epsilon Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform PP2A B subunit isoform B'-epsilon <br />PP2A B subunit isoform B56-epsilon PP2A B subunit isoform PR61-epsilon
背景信息	Protein phosphatase 2A (PP2A) is a family of ubiquitous heterotrimeric proteins that catalyze the removal of phosphate groups from serine and threonine residues. The PP2A enzymes contain core structural (A) and catalytic (C) subunits and variable regulatory B subunits. The B subunits regulate their catalytic activity, as well as dictate substrate specificity and subcellular localization. Recent studies have suggested that B56 epsilon subunits regulate p53-mediated apoptotic pathways, and can induce or suppress apoptosis depending on the cellular context. PP2A enzymes are also regulated by posttranslational modifications and endogenous inhibitors.

产品信息
格式	Purified
控制	NIH/3T3 cell lysate
演示	Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

应用
应用	This Anti-PP2A reg. subunit B56 epsilon (PPP2R5E) Antibody, clone 5A5-1F3 is validated for use in Western Blotting, ICC, Immunoprecipitation for the detection of PP2A reg. subunit B56 epsilon (PPP2R5E).
主要应用	Immunocytochemistry Western Blotting
应用说明	Western Blot Analysis: A 1:1,000 dilution from a representative lot detected PP2A reg. subunit B56 epsilon (PPP2R5E) in 10 µg of U2OS cell lysate and mouse brain tissue lysate. Immunocytochemistry Analysis: A representative lot detected PP2A reg. subunit B56 epsilon (PPP2R5E) in U2OS cells. (Max F. Perutz Laboratories, Medical University of Vienna, Austria). Immunoprecipitation Analysis: A representative lot immunoprecipitated endogenous PP2A reg. subunit B56 epsilon (PPP2R5E) in a panel of U2OS cell lysates expressing the B56 alpha, beta, gamma, delta, and epsilon regulatory subunit of PP2A (Max F. Perutz Laboratories, Medical University of Vienna, Austria).

生物信息
免疫原品种	His-tagged recombinant protein corresponding to human PP2A reg. subunit B56 epsilon (PPP2R5E).
克隆	5A5-1F3
宿主	Mouse
特异性	This antibody is specific for the B56 regulatory subunit of Protein phosphatase 2A (PP2A).
同种型	IgG1κ
品种反应性	MouseHuman
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_006237 NP_006237 ">NP_006237 NP_006237 NP_006237
基因符号	PPR2R5E
纯化方法	Protein G purified
UniProt编号	Q16537

产品使用声明
质量保证	Evaluted by Western Blot in NIH/3T3 cell lysate. Western Blot Analysis: A 1:1,000 dilution from a representative lot detected PP2A reg. subunit B56 epsilon (PPP2R5E) in 10 µg of NIH/3T3 cell lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µL

merck millipore,默克密理博,MABS270,Anti-PP2A reg. subunit B56 epsilon (PPP2R5E) Antibody, clone 5A5-1F3

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