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品种反应性 主要应用 宿主 格式 抗体类型 R, H, M IHC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MABN495 描述 Anti-Aldh1L1 Antibody, clone N103/39 Alternate Names - Aldehyde dehydrogenase family 1 member L1<br />FBP-CI
- Cytosolic 10-formyltetrahydrofolate dehydrogenase
- 10-FTHFDH
- FDH
背景信息 Aldh1L1, also known as 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH), is a multidomain protein that is found in liver cytosol and also serves as a CNS astrocyte marker. Aldh1L1 is comprised of two functionally unrelated domains, an aldehyde dehydrogenase-homologous domain and a folate-binding hydrolase domain. These two domains are thought to be connected by a 100-residue linker. It is known to induce phosphorylation of p53 at Ser6, which is a critical step in stimulating apoptosis. 产品信息 格式 Purified 控制 - Mouse brain tissue lysate
演示 Purified mouse monclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-Aldh1L1, clone N103/39 is an antibody targeting the Aldh1L1 protein, validated for use in WB & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Western Blot Analysis: 0.5 µg/mL from a representative lot detected Aldh1L1 in 10 µg of human brain tissue lysate.
Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Aldh1L1 rat cerebral cortex tissue and human pons/midbrain tissue.
Immunofluorescence Analysis: A representative lot detected Aldh1L1 in rat cortex and cerebellum tissue.生物信息 免疫原品种 Recombinant protein corresponding to rat Aldh1L1. 克隆 N103/39 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 This antibody does not demonstrate cross-reactivity against Aldh1L2. 同种型 IgG1κ 品种反应性 RatHumanMouse Species Reactivity Note Demonstrated to react with Human, Mouse, and Rat. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_071992
基因符号 - Fthfd
- Aldh1l1
纯化方法 Protein G purified UniProt编号 - P28037
产品使用声明 质量保证 Evaluated by Western Blot in mouse brain tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Aldh1L1 in 10 µg of mouse brain tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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