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merck millipore,默克密理博,MABN492,Anti-GABA(B)R1 Protein Antibody, clone N93A/49
产品名称：Anti-GABA(B)R1 Protein Antibody, clone N93A/49
产品型号：MABN492
This GABA(B)R1 Protein antibody is validated for use in WB & IHC for the detection of the GABA(B)R1 Protein protein.
merck millipore,默克密理博,MABN492,Anti-GABA(B)R1 Protein Antibody, clone N93A/49
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M, R IHC, WB M Purified Monoclonal Antibody 描述 产品目录编号 MABN492 描述 Anti-GABA(B)R1 Protein Antibody, clone N93A/49 Alternate Names - Gb1
- Gamma-aminobutyric acid type B receptor subunit 1
- GABA-B receptor 1
- GABA-B-R1
- GABA-BR1
- GABABR1
背景信息 Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates 4 transcript variants. 产品信息 格式 Purified 控制 - Rat microsomal brain tissue
演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl, and 0.05% sodium azide. 应用 应用 This GABA(B)R1 Protein antibody is validated for use in WB & IHC for the detection of the GABA(B)R1 Protein protein. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A representative lot detected GABA(B)R1 in adult rat hippocampus tissue (Prof. J. Trimmer, University of California, Davis).
Western Blotting Analysis: A representative lot detected GABA(B)R1 in adult rat brain tissue and in WT GABA(B)R1 mice, but demonstrated a loss of signal in GABA(B)R1 knockout mice.生物信息 免疫原品种 Recombinant protein corresponding to rat GABA(B)R1. 克隆 N93A/49 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 This antibody does not cross react with GABA(B)R1. 同种型 IgG1κ 品种反应性 MouseRat Species Reactivity Note Demonstrated to react with Rat and Mouse. Other Homologies: Human (97% sequence homology). 抗体类型 Monoclonal Antibody Entrez基因编号 - NP112290
基因符号 - Gabbr1
纯化方法 Protein G purified UniProt编号 - Q9Z0U4
产品使用声明 质量保证 Evaluated by Western Blotting in rat microsomal brain tissue.
Western Blotting: 1 µg/mL of this antibody detected GABA(B)R1 in 10 µg of rat microsomal brain tissue.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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