merck millipore,默克密理博,MABN45,Anti-Tdp43 Antibody, clone 3H8

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merck millipore,默克密理博,MABN45,Anti-Tdp43 Antibody, clone 3H8
产品名称：Anti-Tdp43 Antibody, clone 3H8
产品型号：MABN45
Detect TDP using this mouse monoclonal antibody, Anti-Tdp43 Antibody, clone 3H8 validated for use in western blotting & IHC.

merck millipore,默克密理博,MABN45,Anti-Tdp43 Antibody, clone 3H8

产品介绍

merck millipore,默克密理博,MABN45,Anti-Tdp43 Antibody, clone 3H8

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
R, H, M	IHC, WB	M	Purified	Monoclonal Antibody

描述
产品目录编号	MABN45
描述	Anti-Tdp43 Antibody, clone 3H8
Alternate Names	TAR DNA binding protein-43 TAR DNA-binding protein 43 TDP-43 TDP43
背景信息	TAR DNA-binding protein 43 (Tdp43) belongs to the hnRNP protein family and plays an important role in transcription, pre-mRNA splicing, mRNA stability and mRNA transport. It is involved in splicing of the apolipoprotein A-II and cystic fibrosis transmembrane gene. This protein is highly expressed in the pancreas, placenta, lung, genital tract and spleen. Mutations in Tdp43 have been associated with amyotrophic lateral sclerosis, frontotemporal dementia, Parkinson's disease and Alzheimer's disease.

产品信息
格式	Purified
演示	Purified mouse monoclonal IgG1κ in buffer containing PBS with 0.05% sodium azide with 10% glycerol.

应用
应用	Detect TDP using this mouse monoclonal antibody, Anti-Tdp43 Antibody, clone 3H8 validated for use in western blotting & IHC.
主要应用	Immunohistochemistry Western Blotting
应用说明	Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Tdp43 in human frontal lobe, human cerebellum, and rat cerebellum tissue.

生物信息
免疫原品种	His-tagged recombinant protein corresponding to the N-terminus of human Tdp43.
克隆	3H8
宿主	Mouse
同种型	IgG₁
品种反应性	RatHumanMouse
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_031401
基因符号	TDP43 TARDBP
纯化方法	Protein G purified
UniProt编号	Q13148

产品使用声明
质量保证	Evaluated by Western Blotting in mouse brain nuclear extract tissue lysate. Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Tdp43 in 10 µg of mouse brain nuclear extract tissue lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.