merck millipore,默克密理愽
  • merck millipore,默克密理博,MABF730,Anti-Foxp3 Antibody (mouse), APC, clone 3G3

  • merck millipore,默克密理博,MABF730,Anti-Foxp3 Antibody (mouse), APC, clone 3G3

    产品名称：Anti-Foxp3 Antibody (mouse), APC, clone 3G3
    产品型号：MABF730
    This mouse monoclonal antibody Anti-Foxp3 (mouse), APC & clone 3G3 validated for use in Flow Cytometry for the detection of Foxp3.

    merck millipore,默克密理博,MABF730,Anti-Foxp3 Antibody (mouse), APC, clone 3G3

  • 产品介绍
  • merck millipore,默克密理博,MABF730,Anti-Foxp3 Antibody (mouse), APC, clone 3G3

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    MFCMAPCMonoclonal Antibody
    描述
    产品目录编号 MABF730
    描述 Anti-Foxp3 Antibody (mouse), APC, clone 3G3
    Alternate Names
    • Scurfin
    • Forkhead box protein P3
    背景信息 The 3G3 antibody reacts with mouse Foxp3, a 50-55 kDa transcription factor which is a central regulator of T cell activity and is critical for the development and function of regulatory T cells (Tregs). Foxp3 is expressed at constitutively high levels in Treg cells, which are further identified as being CD4+ CD25+. In resting conventional T cells (CD4+ CD25-) Foxp3 expression is restricted, and upon TCR activation is expressed only transiently and in a small proportion of cells. However, the growth factor TGF-beta has been shown to induce expression of Foxp3 in naïve T cells, driving their development into Foxp3+ Tregs, which are called “induced” or “adaptive” Tregs. These cells are phenotypically similar to so-called “natural” Tregs (CD4+ CD25high Foxp3+) which originate in the thymus and comprise the majority of Treg cells. Tregs are critical for maintaining peripheral tolerance and are implicated in the development of autoimmunity.It is important to review the literature in choosing an antibody for the Foxp3 antigen in flow cytometry, as the potential for high background or non-specific staining may be observed. The 3G3 antibody may be used for intracellular detection of Foxp3 in cells from mouse and Rhesus macaque.
    产品信息
    格式 APC
    演示 Purified Mouse Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide.
    应用
    应用 This mouse monoclonal antibody Anti-Foxp3 (mouse), APC & clone 3G3 validated for use in Flow Cytometry for the detection of Foxp3.
    主要应用
    • Flow Cytometry
    生物信息
    免疫原品种 Immunogen information for this antibody is proprietary information.
    克隆 3G3
    浓缩 0.2 mg/mL
    宿主 Mouse
    同种型 IgG1κ
    品种反应性 Mouse
    抗体类型 Monoclonal Antibody
    基因符号
    • PFoxp3
    纯化方法 Size Exclusion Chromatography
    UniProt编号
    • Q99JB6
    产品使用声明
    质量保证 The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

    Flow Cytometry Analysis: 0.125 μg of this antibody detected Foxp3 in one million C57Bl/6 splenocytes.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
    包装信息
    数量 25 µg

    merck millipore,默克密理博,MABF730,Anti-Foxp3 Antibody (mouse), APC, clone 3G3

上一件merck millipore产品：merck millipore,默克密理博,ABN185,Anti-alpha B-crystallin Antibody
下一件merck millipore产品：merck millipore,默克密理博,OP64F,Anti-p21WAF1 (58-77) (Ab-1) Mouse mAb (EA10) Fluorescein Conjugate


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