merck millipore,默克密理博,676377,Valinomycin, Streptomyces fulvissimus - CAS 2001-95-8

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merck millipore,默克密理博,676377,Valinomycin, Streptomyces fulvissimus - CAS 2001-95-8 - Calbiochem
产品名称：Valinomycin, Streptomyces fulvissimus - CAS 2001-95-8 - Calbiochem
产品型号：676377
A cyclododecadepsi-peptide ionophore antibiotic.

merck millipore,默克密理博,676377,Valinomycin, Streptomyces fulvissimus - CAS 2001-95-8 - Calbiochem

产品介绍

merck millipore,默克密理博,676377,Valinomycin, Streptomyces fulvissimus - CAS 2001-95-8 - Calbiochem

重要规格表

经验配方	CAS号
C₅₄H₉₀N₆O₁₈	2001-95-8

描述
概述	A cyclododecadepsi-peptide ionophore antibiotic. Potassium ionophore of the mobile ion-carrier type that transports alkali metal ions across artificial or biological lipid membranes. Induces K⁺ conductivity in cell membranes at concentrations as low as 10^-8 M. Often used in membrane electrode systems for determining K⁺ concentration. Uncouples oxidative phosphorylation by binding to sites on membranes rich in sulfhydryl groups. Induces apoptosis in murine thymocytes. Also reported to inhibit NGF-induced neuronal differentiation.
产品目录编号	676377
品牌系列	Calbiochem®

参考
参考	Harada, H., et al. 1994. Biochim. Biophys. Acta 1220, 310. Luvisetto, S., et al. 1994. Biochim. Biophys. Acta 1186, 12. Orlov, V.N., et al. 1994. FEBS Lett. 345, 104. Acra, S., et al. 1993. Am. J. Physiol. 264, G45. Cornet, M., et al. 1993. J. Membr. Biol. 131, 55. Deckers, C.L., et al. 1993. Exp. Cell Res. 208, 362. Dimroth, P., and Thomer, A. 1993. Biochemistry 32, 1734. Opanasenko, V.K., et al. 1992. FEBS Lett. 307, 280. Pape, P.C., et al. 1992. J. Physiol. 449, 219. Ahmed, S., and Booth, I.R. 1983. Biochem. J. 212, 105. Lerner, A., et al. 1982. FEBS Lett. 146, 9.

参考

Harada, H., et al. 1994. Biochim. Biophys. Acta 1220, 310.
Luvisetto, S., et al. 1994. Biochim. Biophys. Acta 1186, 12.
Orlov, V.N., et al. 1994. FEBS Lett. 345, 104.
Acra, S., et al. 1993. Am. J. Physiol. 264, G45.
Cornet, M., et al. 1993. J. Membr. Biol. 131, 55.
Deckers, C.L., et al. 1993. Exp. Cell Res. 208, 362.
Dimroth, P., and Thomer, A. 1993. Biochemistry 32, 1734.
Opanasenko, V.K., et al. 1992. FEBS Lett. 307, 280.
Pape, P.C., et al. 1992. J. Physiol. 449, 219.
Ahmed, S., and Booth, I.R. 1983. Biochem. J. 212, 105.
Lerner, A., et al. 1982. FEBS Lett. 146, 9.

产品信息
CAS号	2001-95-8
具有ATP竞争性	N
形式	White crystalline solid
Hill配方	C₅₄H₉₀N₆O₁₈
化学配方	C₅₄H₉₀N₆O₁₈
Molar Mass	1111.3
可逆	N
结构配方图像

生物信息
主靶	NGF-induced neuronal differentiation
纯度	≥93% by HPLC

理化信息
细胞可渗透	N
溶解度	Acetic Acid, Chloroform, DMSO, or Ether

GHS安全信息
RTECS	YV9468000

安全信息
R相	R: 26/27/28 Very toxic by inhalation, in contact with skin and if swallowed.
S相	S: 22-36/37/39-45 Do not breathe dust. Wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Highly Toxic
有害材料注意事项：	Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
储存	+15°C to +30°C
无需冷冻	No