merck millipore,默克密理博,MABF542,Anti-CD127 (IL-7Ra) Antibody (mouse), APC, clone R34-34

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	FC	M	APC	Monoclonal Antibody

描述
产品目录编号	MABF542
描述	Anti-CD127 (IL-7Ra) Antibody (mouse), APC, clone R34-34
Alternate Names	CD antigen CD127 Interleukin-7 receptor subunit alpha IL-7 receptor subunit alpha IL-7R subunit alpha IL-7R-alpha IL-7RA CDw127
背景信息	The R34-34 antibody is specific for human CD127, a cell surface protein also known as the Interleukin-7 Receptor alpha chain, or IL-7R alpha. CD127 is typically expressed at the cell surface as a heterodimer with the common gamma chain (CD132). This complex acts as the functional receptor for IL-7, a cytokine important in T and B cell development, and in mature T cell homeostasis. A second cytokine known as Thymic Stromal Lymphopoietin (TSLP) also binds to a receptor complex of CD127 and the TSLPR chain to trigger activation of dendritic cells, and is involved in B cell development, allergy and autoimmunity. The R34-34 antibody may be used as a phenotypic marker for CD127 on immature B cells, on subsets of thymocytes which are double negative (CD4-CD8- ) or single positive (CD4+ or CD8+), and at low levels on mature, peripheral T cells. CD127 is a key marker, when used in combination with CD4 and CD25, to distinguish Treg and effector/memory Treg populations known as T(REM), whereas certain populations of Foxp3+ /CD25+ T cells lacking CD127 have been associated with impaired suppressive function (Bikker et al. 2012. Rheumatology, 51: 996-1005)

产品信息
格式	APC
演示	Purified Mouse Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide.

应用
应用	This mouse monoclonal antibody Anti-CD127 (IL-7Ra) (mouse), APC & clone R34-34 validated for use in Flow Cytometry for the detection of CD127 (IL-7Ra).
主要应用	Flow Cytometry

生物信息
免疫原品种	Immunogen information for this antibody is proprietary information.
克隆	R34-34
浓缩	5 μL (0.5 μg)/test
宿主	Mouse
同种型	IgG1κ
品种反应性	Human
抗体类型	Monoclonal Antibody
基因符号	IL7R
纯化方法	Size Exclusion Chromatography
UniProt编号	P16871

产品使用声明
质量保证	The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. Flow Cytometry Analysis: 0.5 μg of this antibody detected CD127 (IL-7Ra) in one million human peripheral blood lymphocytes.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

包装信息
数量	25 tests

merck millipore,默克密理博,MABF542,Anti-CD127 (IL-7Ra) Antibody (mouse), APC, clone R34-34

whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech