merck millipore,默克密理愽
  • merck millipore,默克密理博,MABE426,Anti-Sirt1(Sir2) Antibody, clone 3-10, rabbit monoclonal

  • merck millipore,默克密理博,MABE426,Anti-Sirt1(Sir2) Antibody, clone 3-10, rabbit monoclonal

    产品名称：Anti-Sirt1(Sir2) Antibody, clone 3-10, rabbit monoclonal
    产品型号：MABE426
    Anti-Sirt1(Sir2) Antibody, clone 3-10 is a highly specific rabbit monoclonal antibody, that targets SIRT1 & has been tested in western blotting & IHC.

    merck millipore,默克密理博,MABE426,Anti-Sirt1(Sir2) Antibody, clone 3-10, rabbit monoclonal

  • 产品介绍
  • merck millipore,默克密理博,MABE426,Anti-Sirt1(Sir2) Antibody, clone 3-10, rabbit monoclonal

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    MIHC, WBRbCulture SupernatantMonoclonal Antibody
    描述
    产品目录编号 MABE426
    描述 Anti-Sirt1(Sir2) Antibody, clone 3-10, rabbit monoclonal
    Alternate Names
    • 75SirT1
    • NAD-dependent protein deacetylase sirtuin-1
    • Regulatory protein SIR2 homolog 1
    • SIR2-like protein 1
    • SIR2alpha
    • Sir2
    • mSIR2a
    • SirtT1 75 kDa fragment
    背景信息 Sirtuins are a family of closely related enzymes named after the yeast gene Sir2 (silent mating type information regulation 2). Members of the Sirtuin family have been found in nearly all organisms studied. Sirtuins are hypothesized to play a key role in an organism's response to stresses (such as heat or starvation) and to be responsible for the lifespan-extending effects of calorie restriction. Sirtuins act by removing acetyl groups from proteins in the presence of NAD+; they are thus classified as "NAD+-dependent deacetylases". Sirtuins have been implicated in the regulation of aging, transcription, apoptosis and stress resistance. Sirt1 (also known as Sirtuin 1, Sir2L1, and Sir2a), the mammalian homolog of yeast Sir2, has been shown to deacetylate and thereby deactivate the p53 protein to regulate cellular processes.
    产品信息
    格式 Culture Supernatant
    控制
    • NIH-3T3 cell lysate
    演示 Rabbit monoclonal IgG in buffer containing 0.05% sodium azide.
    应用
    应用 Anti-Sirt1(Sir2) Antibody, clone 3-10 is a highly specific rabbit monoclonal antibody, that targets SIRT1 & has been tested in western blotting & IHC.
    主要应用
    • Immunohistochemistry
    • Western Blotting
    应用说明 Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Sirt1(Sir2) in mouse frontal lobe, mouse adrenal gland, and mouse hippocampus tissues.
    生物信息
    免疫原品种 His-tagged recombinant protein corresponding to mouse Sirt1(Sir2).
    克隆 3-10
    宿主 Rabbit
    同种型 IgG
    品种反应性 Mouse
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_062786
    基因符号
    • Sir2l1
    • Sirt1
    纯化方法 Unpurified
    UniProt编号
    • Q923E4
    产品使用声明
    质量保证 Evaluated by Western Blotting in NIH-3T3 cell lysate.

    Western Blotting Analysis: A 1:2,000 dilution of this antibody detected Sirt1(Sir2) in 10 µg of NIH-3T3 cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at -20°C from date of receipt.
    Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,MABE426,Anti-Sirt1(Sir2) Antibody, clone 3-10, rabbit monoclonal

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下一件merck millipore产品：merck millipore,默克密理博,658411,InSolution™ AG490 - Calbiochem


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