- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 Xn, H, M, R WB M Purified Monoclonal Antibody 描述 产品目录编号 05-657 品牌系列 Upstate
商名 - Upstate
描述 Anti-PP2A Antibody, A subunit, clone 4G7 产品信息 格式 Purified 演示 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30% 应用 应用 Anti-PP2A Antibody, A subunit, clone 4G7 is an antibody against PP2A for use in WB. 主要应用 - Western Blotting
应用说明 Not recommended for IP 生物信息 免疫原品种 Peptide corresponding to amino acids 6-19 (GDDSLYPIAVLIDE) of human Protein Phosphatase 2A, A subunit 克隆 4G7 宿主 Mouse 特异性 PP2A A subunit, α and β isoforms 同种型 IgG1 品种反应性 XenopusHumanMouseRat 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_002716
Entrez基因汇总 This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. 基因符号 - MGC786
- PPP2R1A
- PR65A
纯化方法 Protein G chromatography UniProt编号 - P30153
UniProt汇总 FUNCTION: SwissProt: P30153 # The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit.
SIZE: 589 amino acids; 65309 Da
SUBUNIT: PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules. Interacts with IPO9.
DOMAIN: SwissProt: P30153 Each HEAT repeat appears to consist of two alpha helices joined by a hydrophilic region, the intrarepeat loop. The repeat units may be arranged laterally to form a rod-like structure.
SIMILARITY: Belongs to the phosphatase 2A regulatory subunit A family. & Contains 15 HEAT repeats.产品使用声明 质量保证 routinely evaluated by immunoblot on RIPA lysates from NIH-3T3, HEK293, or HeLa cells 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 2 years at -20°C 包装信息 数量 200 µg
上一件merck millipore产品：merck millipore,默克密理博,658411,InSolution™ AG490 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,SF-433,IL-6; Human, Cyanine 3, RNA Detection Probe,SmartFlare
相关产品
merck millipore,默克密理博,LSKSIS500,Montage 注射液，0.5 L
merck millipore,默克密理博,HTS129RTA,Ready-to-Assay™ D5 Dopamine Receptor Frozen Cells
merck millipore,默克密理博,MABN92,Anti-Iba1/AIF1 Antibody
merck millipore,默克密理博,MABE426,Anti-Sirt1(Sir2) Antibody, clone 3-10, rabbit monoclonal
merck millipore,默克密理博,658411,InSolution™ AG490 - Calbiochem
merck millipore,默克密理博,SF-433,IL-6; Human, Cyanine 3, RNA Detection Probe,SmartFlare
merck millipore,默克密理博,SF-1542,MBL2; Human, Cyanine 5 RNA Detection Probe,SmartFlare
merck millipore,默克密理博,MABE325,Anti-p21WAF1 Antibody, clone EA10
