merck millipore,默克密理愽
  • merck millipore,默克密理博,MABC985,Anti-TRAF4 Antibody, clone 5MLN-2H1

  • merck millipore,默克密理博,MABC985,Anti-TRAF4 Antibody, clone 5MLN-2H1

    产品名称：Anti-TRAF4 Antibody, clone 5MLN-2H1
    产品型号：MABC985
    This Anti-TRAF4 Antibody, clone 5MLN-2H1 is validated for use in Western Blotting and Immunohistochemistry and Immunocytochemistry for the detection of TRAF4.

    merck millipore,默克密理博,MABC985,Anti-TRAF4 Antibody, clone 5MLN-2H1

  • 产品介绍
  • merck millipore,默克密理博,MABC985,Anti-TRAF4 Antibody, clone 5MLN-2H1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, HICC, WB, IHCMAscitesMonoclonal Antibody
    描述
    产品目录编号 MABC985
    描述 Anti-TRAF4 Antibody, clone 5MLN-2H1
    Alternate Names
    • RING finger protein 83
    • TNF receptor-associated factor 4
    • Cysteine-rich domain associated with RING and Traf domains protein 1
    • Metastatic lymph node gene 62 protein
    • MLN 62
    背景信息 TNF receptor-associated factor 4 (TRAF4), also known as Cysteine-rich domain associated with RING and Traf domains protein 1 (CART1), Metastatic lymph node gene 62 protein (MLN 62), and RING finger protein 83 (RNF83), is an adapter protein and signal transducer that links members of the TNF family to different signaling pathways. As such TRAF4 plays a role in the activation of the NF-kappa- and JNK signaling as well as a player in apoptosis and cell survival pathways. In development, TRAF4 is necessary for proper skeleton development and lung development. TRAF4 is localized in the perinuclear region of the cell as well as other locations including cell junctions where it is associated with various cytoskeletal elements. TRAF4 is expressed in the epithelial cells of thymus, respiratory tract, salivary gland, and esophagus. TRAF4 expression is regulated via the ubiquitin proteasome system and is a polyubiquitin target protein.
    产品信息
    格式 Ascites
    演示 Mouse monoclonal IgG1 ascites without preservatives.
    应用
    应用 This Anti-TRAF4 Antibody, clone 5MLN-2H1 is validated for use in Western Blotting and Immunohistochemistry and Immunocytochemistry for the detection of TRAF4.
    主要应用
    • Immunocytochemistry
    • Western Blotting
    • Immunohistochemistry
    应用说明 Imunnohistochemistry Analysis: A representative lot of this antibody detected TRAF4 in multiple human cancer tissues (Camilleri-Broet. S., et al. (2007) Oncogene. 26:142-147).

    Imunnohistochemistry Analysis: A representative lot of this antibody detected TRAF4 in Breast cancer tissue (Kedinger, V., et. al. (2008) PLoS ONE. 3(10):e3518).

    Immunocytochemistry Analysis: A representative lot of this antibody detected TRAF4 in MCF-10A cells and tranfected HeLa cells (Kedinger, V., et. al. (2008) PLoS ONE. 3(10):e3518).
    生物信息
    免疫原品种 Linear peptide corresponding to Human TRAF4.
    克隆 clone 5MLN-2H1
    浓缩 Please refer to lot specific datasheet.
    宿主 Mouse
    特异性 This antibody detects TRAF4 and is cited in publications as both clone 5MLN-2H1 and clone 2H1.
    同种型 IgG1
    品种反应性 MouseHuman
    Species Reactivity Note Human, Mouse.
    Predicted to react with Rat based on 100% sequence homology.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NP_004286
    基因符号
    • RNF83
    • TRAF4
    • CART1
    • MLN62
    纯化方法 Unpurified
    UniProt编号
    • Q9BUZ4
    产品使用声明
    质量保证 Evaluated by Western Blotting in HeLa cell lysate.

    Western Blotting Analysis: A 1:1000 dilution of this antibody detected TRAF4 in 10 µg of HeLa cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at -20°C from date of receipt.
    Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,MABC985,Anti-TRAF4 Antibody, clone 5MLN-2H1

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下一件merck millipore产品：merck millipore,默克密理博,SF-1040,MBP; Human, Cyanine 3 RNA Detection Probe,SmartFlare


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