merck millipore,默克密理博,MABC94,Anti-Sphingosine 1-phosphate receptor 1 (S1P1) Antibody, clone 8B7.1

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
R, H, M	IHC, WB	M	Purified	Monoclonal Antibody

描述
产品目录编号	MABC94
描述	Anti-Sphingosine 1-phosphate receptor 1 (S1P1) Antibody, clone 8B7.1
Alternate Names	CD363 Sphingosine 1-phosphate receptor 1 S1P receptor 1 S1P1 Endothelial differentiation G-protein coupled receptor 1 Sphingosine 1-phosphate receptor Edg-1 S1P receptor Edg-1
背景信息	Sphingosine 1-phosphate receptor 1(S1PR1 or S1P1), otherwise known as EDG1, is a G-protein coupled receptor which is activated by lysosphingolipid sphingosine 1-phosphate (S1P) and lysophosphatidic acid (LPA). It is coupled to Gi-protein and MAP kinase signaling pathways, and may cooperate with other S1P receptors to regulate various cellular processes such as differentiation, actin remodeling, and migration. S1P1 is expressed in epithelial cells, fibroblasts, melanocytes, and smooth muscle cells.

产品信息
格式	Purified
控制	Mouse brain tissue lysate
演示	Purified mouse monoclonal IgG1κ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

应用
应用	This Anti-Sphingosine 1-phosphate receptor 1 (S1P1) Antibody, clone 8B7.1 is validated for use in Western Blotting, IHC for the detection of Sphingosine 1-phosphate receptor 1 (S1P1).
主要应用	Immunohistochemistry Western Blotting
应用说明	Western Blot Analysis: A 1:500 dilution from a representative lot detected Sphingosine 1-phosphate receptor 1 (S1P1) in human brain tissue lysate. Immunohistochemistry Analysis: A 1:300 dilution from a representative lot detected Sphingosine 1-phosphate receptor 1 (S1P1) in rat choroid plexus tissue.

生物信息
免疫原品种	GST-tagged recombinant protein corresponding to mouse Sphingosine 1-phosphate receptor 1 (S1P1).
克隆	8B7.1
宿主	Mouse
同种型	IgG1κ
品种反应性	RatHumanMouse
Species Reactivity Note	Demonstrated to react with Mouse, Human, and Rat.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_001391
基因符号	EDG1 S1PR1 CHEDG1
纯化方法	Protein G purified
UniProt编号	P21453

产品使用声明
质量保证	Evaluated by Western Blot in mouse brain tissue lysate. Western Blot Analysis: A 1:1,000 diluiton of this antibody detected Sphingosine 1-phosphate receptor 1 (S1P1) in 10 µg of mouse brain tissue lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µL

merck millipore,默克密理博,MABC94,Anti-Sphingosine 1-phosphate receptor 1 (S1P1) Antibody, clone 8B7.1

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