merck millipore,默克密理博,MAB5504A4,Anti-Vesicular Glutamate Transporter 2 Antibody, Alexa Fluor 488,MAB5504A4

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Merck Millipore 默克密理愽

merck millipore,默克密理博,MAB5504A4,Anti-Vesicular Glutamate Transporter 2 Antibody, Alexa Fluor 488,MAB5504A4
产品名称：Anti-Vesicular Glutamate Transporter 2 Antibody, Alexa Fluor 488, MAB5504A4
产品型号：MAB5504A4

merck millipore,默克密理博,MAB5504A4,Anti-Vesicular Glutamate Transporter 2 Antibody, Alexa Fluor 488,MAB5504A4

品种反应性	主要应用	宿主	格式	抗体类型
H, M, R	IHC	M	AlexaFluor®488	Monoclonal Antibody

描述
产品目录编号	MAB5504A4
描述	Anti-Vesicular Glutamate Transporter 2 Antibody, Alexa Fluor® 488 \| MAB5504A4
Alternate Names	Solute carrier family 17 member 6 Vesicular glutamate transporter 2 VGluT2 Differentiation-associated BNPI Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter
背景信息	Vesicular Glutamate Transporter 2 (VGLUT2) is a sodium dependent inorganic phosphate cotransporter that is involved in the calcium dependent glutamate release from astrocytes. It is expressed in only a subset of neurons, localized to synaptic vesicles, at synapses exhibiting classical excitatory features. VGLUT2 mRNA is found in brain regions that lack VGLUT1, a related protein also displaying sodium dependent inorganic phosphate cotransporter activity.

产品信息
格式	AlexaFluor®488
控制	Adult mouse brain tissue
演示	Purified mouse monoclonal IgG1 conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

应用
主要应用	Immunohistochemistry

生物信息
免疫原品种	Recombinant protein from rat VGLUT2.
克隆	8G9.2
宿主	Mouse
同种型	IgG1
品种反应性	HumanMouseRat
Species Reactivity Note	Demonstrated to react with Mouse and Rat. Predicted to react with Human based on 100% sequence homology.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_445879
Entrez基因汇总	Na+-dependent inorganic phosphate cotransporter; involved in Ca2+-dependent glutamate release from astrocytes [RGD].
基因符号	VGLUT2 Slc17a6 Dnpi Vglut2
纯化方法	Protein A purified
UniProt编号	Q9JI12
UniProt汇总	FUNCTION: Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also play a role in the endocrine glutamatergic system of other tissues such as pineal gland and pancreas. May also mediate the transport of inorganic phosphate. SUBCELLULAR LOCATION: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane. Membrane; Multi-pass membrane protein (Potential). Cell junction, synapse, synaptosome. TISSUE SPECIFICITY: Expressed in brain (at protein level). Expressed in brainstem, deep nuclei, septal nuclei, nuclei of the diagonal band, frontal cortex, hypothalamus, midbrain, parietal cortex and temporal cortex. Also expressed in pineal gland and islets of Langerhans. SIMILARITY: Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily. SIZE: 582 amino acids; 64392 Da

产品使用声明
质量保证	Evaluated by Immunohistochemistry in adult mouse brain tissue. Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected Vesicular Glutamate Transporter 2 in adult mouse brain tissue.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

包装信息
数量	100 µL

merck millipore,默克密理博,MAB5504A4,Anti-Vesicular Glutamate Transporter 2 Antibody, Alexa Fluor 488,MAB5504A4

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