• merck millipore,默克密理博,MAB3864,Anti-DNA/Histone H1 Antibody
  • merck millipore,默克密理博,MAB3864,Anti-DNA/Histone H1 Antibody

    产品名称:Anti-DNA/Histone H1 Antibody
    产品型号:MAB3864
    Anti-DNA/Histone H1 Antibody is a high quality Mouse Monoclonal Antibody for the detection of DNA/Histone H1 & has been validated in ELISA, FC, ICC & IHC.

    merck millipore,默克密理博,MAB3864,Anti-DNA/Histone H1 Antibody

  • 产品介绍
  • merck millipore,默克密理博,MAB3864,Anti-DNA/Histone H1 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    AIHC, ELISA, FC, ICCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB3864
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-DNA/Histone H1 Antibody
    产品信息
    格式 Purified
    演示 Protein A purified culture supernatant. Liquid in PBS
    应用
    应用 Anti-DNA/Histone H1 Antibody is a high quality Mouse Monoclonal Antibody for the detection of DNA/Histone H1 & has been validated in ELISA, FC, ICC & IHC.
    主要应用
    • Immunohistochemistry
    • ELISA
    • Flow Cytometry
    • Immunocytochemistry
    应用说明 Immunocytochemistry: 5-10 μg/mL on 2% paraformaldehyde fixed cells (10 minutes at room temperature)

    Immunohistochemistry: 5-10 μg/mL on paraformaldehyde or B5 fixed tissue sections.

    Flow cytometry: 5-10 μg/mL using 2% paraformaldehyde fixed cells.

    ELISA, direct and indirect

    Optimal working dilutions must be determined by end user.

    STAINING PATTERN:

    Nuclear staining observed. Dense staining of nuclei. No staining of nucleoli.
    生物信息
    免疫原品种 Human Raji cell nuclei
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Reacts with DNA/Histone 1. The antibody can be used to stain nuclei of all species and to identify necrosis. By immunohistochemistry, the antibody shows dense staining of nuclei with no staining of nucleoli observed.
    同种型 IgG2a
    品种反应性 All
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_005321.2
    Entrez基因汇总 Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
    基因符号
    • MGC116819
    • HIST1H1E
    • H1.4
    • dJ221C16.5
    • H1F4
    UniProt编号
    • P10412
    UniProt汇总 FUNCTION: SwissProt: P10412 # Histones H1 are necessary for the condensation of nucleosome chains into higher order structures.
    SIZE: 219 amino acids; 21865 Da
    SUBCELLULAR LOCATION: Nucleus.
    SIMILARITY: SwissProt: P10412 ## Belongs to the histone H1/H5 family.
    MISCELLANEOUS: This variant accounts for 60% of histone H1.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months from date of receipt. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,MAB3864,Anti-DNA/Histone H1 Antibody

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