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merck millipore,默克密理博,MAB3775,Anti-Cdc20 Antibody, clone AR12
产品名称：Anti-Cdc20 Antibody, clone AR12
产品型号：MAB3775
Anti-Cdc20 Antibody, clone AR12 is a Mouse Monoclonal Antibody for detection of Cdc20 also known as Cell Division Cycle Protein 20 Homolog p55cdc & has been validated in IF & IP.
merck millipore,默克密理博,MAB3775,Anti-Cdc20 Antibody, clone AR12
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IP, IF M Purified Monoclonal Antibody 描述 产品目录编号 MAB3775 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Cdc20 Antibody, clone AR12 Alternate Names - Cell Division Cycle Protein 20 Homolog, p55cdc
- Cell Division Cycle Protein 20 Homolog
产品信息 格式 Purified 演示 Purified immunoglobulin. Liquid in 0.02M phosphate buffer, 0.25M NaCl, pH 7.6, with 0.1% sodium azide. 应用 应用 Anti-Cdc20 Antibody, clone AR12 is a Mouse Monoclonal Antibody for detection of Cdc20 also known as Cell Division Cycle Protein 20 Homolog p55cdc & has been validated in IF & IP. 主要应用 - Immunoprecipitation
- Immunofluorescence
应用说明 Immunofluorescence
Immunoprecipitation
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Human Cdc20 recombinant protein 克隆 AR12 宿主 Mouse 特异性 Recognizes human Cdc20 同种型 IgG1 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_001255.2
Entrez基因汇总 CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation. 基因符号 - bA276H19.3
- CDC20
- CDC20A
- MGC102824
- p55CDC
- P55CDC-LSB
UniProt编号 - Q12834
UniProt汇总 FUNCTION: SwissProt: Q12834 # Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1. In metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates.
SIZE: 499 amino acids; 54723 Da
SUBUNIT: Found in a complex with CDC20, CDC27, SPATC1 and TUBG1. Interacts with SPATC1 (By similarity). Interacts with MAD2L1. The phosphorylated form interacts with APC/C.
DEVELOPMENTAL STAGE: Synthesis is initiated at G1/S, protein level peaks in M phase and protein is abruptly degraded at M/G1 transition.
PTM: Phosphorylated during mitosis, probably by maturation promoting factor (MPF).
SIMILARITY: SwissProt: Q12834 ## Belongs to the WD repeat CDC20/Fizzy family. & Contains 7 WD repeats.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt. 包装信息 数量 100 µg
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